Lamotrigine and Weight gain - unintentional for Men aged 60+ (a phase IV clinical study of FDA data)

Summary:

Weight gain - unintentional is found for men aged 60+ who take Lamotrigine (lamotrigine). This study is created by eHealthMe based on reports of 3,676 men aged 60+ from the FDA, and is updated regularly. The information that eHealthMe analyzes includes:

Time on Lamotrigine when people have Weight gain - unintentional
Top conditions
Top co-used drugs
Top other side effects

On Apr, 18, 2026

3,676 men aged 60+ reported to have side effects when taking Lamotrigine.
Among them, 42 people (1.14%) have Weight gain - unintentional

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,633 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Weight gain - unintentional?

Weight gain - unintentional is found to be associated with 3,579 drugs and 4,089 conditions by eHealthMe. Check the latest studies of Weight gain - unintentional.

Number of reports submitted per year:

Could Lamotrigine cause Weight gain - unintentional in men aged 60+?

Severity of Weight gain - unintentional

n/a

How people recovered from Weight gain - unintentional

n/a

Top conditions involved for these people *:

You may use this to check any potential undetected conditions.

Depression: 7 people, 16.67%
Urination - Painful: 4 people, 9.52%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 9.52%
Blood Uric Acid Increased: 4 people, 9.52%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 9.52%
Headache (pain in head): 4 people, 9.52%
Musculoskeletal Discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 4 people, 9.52%
Nausea (feeling of having an urge to vomit): 4 people, 9.52%
Primary Myelofibrosis (primary disorder of the bone marrow): 4 people, 9.52%
Hypersensitivity: 4 people, 9.52%

Top co-used drugs for these people *:

You may use this to check any potential interacting drugs.

Top other side effects for these people *:

You may use this to check any potential undetected side effects.

High Blood Pressure: 10 people, 23.81%
Drug Ineffective: 8 people, 19.05%
Dyspnea (difficult or laboured breathing): 7 people, 16.67%
Weakness: 7 people, 16.67%
Fatigue (feeling of tiredness): 7 people, 16.67%
Weight Decreased: 6 people, 14.29%
Tremor (trembling or shaking movements in one or more parts of your body): 6 people, 14.29%
Memory Loss: 6 people, 14.29%
White Blood Cell Count Decreased: 6 people, 14.29%
Nausea (feeling of having an urge to vomit): 6 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Lamotrigine and have Weight gain - unintentional?

- Check whether Weight gain - unintentional is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related publications that referenced our studies:

Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .

Related studies:

Lamotrigine and Weight gain - unintentional

How the study uses the data?

The study is based on (applicable) gender, age, lamotrigine (the active ingredients of Lamotrigine) and Lamotrigine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.