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How effective is Plaquenil for Systemic Lupus Erythematosus? (a real world drug study)

Summary:

Overall ratings: 3/5
Long term ratings: 3.3/5

This is a phase IV clinical study of how effective Plaquenil (hydroxychloroquine sulfate) is for Systemic lupus erythematosus and for what kind of people. The study is created by eHealthMe from 510 Plaquenil users and is updated continuously.

What is Plaquenil?

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. eHealthMe is studying from 91,018 Plaquenil users. Check the latest studies of Plaquenil.

What is Systemic lupus erythematosus?

Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue) is found to be associated with 1,089 drugs and 1,641 conditions by eHealthMe. Check the latest studies of Systemic lupus erythematosus.

On Jun, 15, 2026

510 people are studied for taking Plaquenil in Systemic lupus erythematosus

Overall effectiveness (number of people):

Does Plaquenil work for your Systemic lupus erythematosus (overall)?

Long term (1+ years) effectiveness (number of people):

Does Plaquenil work for your Systemic lupus erythematosus (long term)?

Plaquenil effectiveness for Systemic lupus erythematosus (number of people):

Overall:
  • not at all: 45
  • somewhat: 133
  • moderate: 159
  • high: 128
  • very high: 45
Long Term:
  • not at all: 8
  • somewhat: 60
  • moderate: 114
  • high: 103
  • very high: 39

Gender of people who take Plaquenil for Systemic lupus erythematosus *:

  • female: 95.29 %
  • male: 4.71 %

Age of people who take Plaquenil for Systemic lupus erythematosus *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.96 %
  • 20-29: 11.37 %
  • 30-39: 21.57 %
  • 40-49: 28.43 %
  • 50-59: 23.53 %
  • 60+: 13.14 %

Who find Plaquenil more effective for Systemic Lupus Erythematosus?

Gender of people who take Plaquenil for Systemic lupus erythematosus *:

  • female: 95.38 %
  • male: 4.62 %

Age of people who take Plaquenil for Systemic lupus erythematosus *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.16 %
  • 20-29: 9.83 %
  • 30-39: 17.92 %
  • 40-49: 23.7 %
  • 50-59: 26.01 %
  • 60+: 21.39 %

* Approximation only. Some reports may have incomplete information.

Do you take Plaquenil?

- You can start a phase IV clinical trial to monitor Plaquenil safety and effectiveness.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related publications that referenced our studies:

Related studies

Alternative drugs to, pros and cons of:

Treatments, associated drugs and conditions:

How the study uses the data?

The study is based on hydroxychloroquine sulfate (the active ingredients of Plaquenil) and Plaquenil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study neither.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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