Co-Codamol Vs. Codeine for a male patient aged 46 (an AI-powered real world drug study)

Summary:

This is a personalized comparison of Co-Codamol, Codeine for a man aged 46. The study is created by eHealthMe based on reports from the FDA and eHealthme.


On Jun, 09, 2026

3,429 males aged 46 (±5) who take Co-Codamol, Codeine and have adverse effects are studied.


Number of reports submitted per year:

Co-Codamol, Codeine for a male patient aged 46.

Information of the patient in this study:

  • Age: 46
  • Gender: male

What are the drugs?

What is the reason to compare the drugs?

  • Hernia - inguinal (a hernia is a lump that results from a part of the intestine (bowel) slipping through a weakness in the abdominal wall) is found to be associated with 1,776 drugs and 1,499 conditions by eHealthMe. Check the latest studies of Hernia - inguinal.

eHealthMe real world results:

Most common side effects:

Co-Codamol:

  1. Nausea (feeling of having an urge to vomit)
  2. Pyrexia (fever)
  3. Anxiety
  4. Arthralgia (joint pain)
  5. Dizziness
  6. Weight Decreased
  7. Drug Ineffective
  8. Dyspnoea (difficult or laboured respiration)
  9. Vomiting
  10. Abdominal Pain

Codeine:

  1. Drug Abuse
  2. Substance Abuse
  3. Nausea (feeling of having an urge to vomit)
  4. Drug Ineffective
  5. Arthralgia (joint pain)
  6. Death
  7. Drug Hypersensitivity
  8. Rash
  9. Fatigue (feeling of tiredness)
  10. Anxiety

Most common side effects experienced by people in long term (1+ years) use:

Co-Codamol:

  1. Optic Neuritis (optic nerve inflammation)
  2. Anxiety
  3. Osteopenia (a condition where bone mineral density is lower than normal)
  4. Emotional Distress
  5. Dizziness
  6. Polyarthritis (arthritis which involves 5 or more joints simultaneously)
  7. Nausea (feeling of having an urge to vomit)
  8. Chronic Kidney Disease
  9. Hepatic Failure (liver failure)
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

Codeine:

  1. Pancreatitis (inflammation of pancreas)
  2. Hyperthyroidism (over activity of the thyroid gland)
  3. Abdominal Pain
  4. Urticaria Chronic (long lasting rash of round, red welts on the skin that itch intensely)
  5. Tenesmus (a feeling of constantly needing to pass stools, despite an empty colon)
  6. Tachycardia Irregular (irregular, uneven, or skipping beats with increased heart rate)
  7. Sleep Apnea (a type of sleep disorder characterized by pauses in breathing)
  8. Pericardial Effusion (fluid around the heart)
  9. Lichen Planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash)
  10. Depression

Drug effectiveness:

Co-Codamol:

  • not at all: 3.39 %
  • somewhat: 33.9 %
  • moderate: 25.42 %
  • high: 32.2 %
  • very high: 5.08 %

Codeine:

  • not at all: 0 %
  • somewhat: 26.09 %
  • moderate: 39.13 %
  • high: 21.74 %
  • very high: 13.04 %



How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

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How the study uses the data?

The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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