Flecainide Acetate Vs. Clonidine Hydrochloride Vs. Metromidol for a male patient aged 77 (an AI-powered real world drug study)

A-Fib (most common type of arrhythmia):

• Flecainide Acetate: 2.53 %
• Clonidine Hydrochloride: 0.2 %
• Metromidol: 1.22 %

Flecainide Acetate:

1. Dyspnoea (difficult or laboured respiration)
2. Dizziness
3. Fatigue (feeling of tiredness)
4. Asthenia (weakness)
5. Diarrhoea
6. Malaise (a feeling of general discomfort or uneasiness)
7. Nausea (feeling of having an urge to vomit)
8. Drug Ineffective
9. Hypotension (abnormally low blood pressure)
10. Rash

Clonidine Hydrochloride:

1. Toxic Epidermal Necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
2. Fatigue (feeling of tiredness)
3. Dizziness
4. Dyspnoea (difficult or laboured respiration)
5. Asthenia (weakness)
6. Diarrhoea
7. Renal Failure (kidney dysfunction)
8. Pain
9. Nausea (feeling of having an urge to vomit)
10. Malaise (a feeling of general discomfort or uneasiness)

Metromidol:

1. Sepsis (a severe blood infection that can lead to organ failure and death)
2. Nausea (feeling of having an urge to vomit)
3. Vomiting
4. Abdominal Pain
5. General Physical Health Deterioration (weak health status)
6. Abdominal Distension
7. Constipation
8. Ascites (accumulation of fluid in the abdominal cavity)
9. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
10. Cardiogenic Shock (inadequate circulation of blood)

Flecainide Acetate:

1. Interstitial Lung Disease
2. Drug Ineffective
3. Coronary Artery Stenosis (narrowing of coronary artery)
4. Angina Unstable (chest pain due to ischemia of the heart muscle- unstable)
5. Coronary Artery Disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
6. Pyrexia (fever)
7. Fall
8. Left Ventricular Dysfunction
9. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
10. Vitreous Haemorrhage (intraocular (inside the eye) bleeding)

Clonidine Hydrochloride:

1. Blood Pressure Decreased
2. Coronary Artery Stenosis (narrowing of coronary artery)
3. Anaemia (lack of blood)
4. Overdose
5. Blood Lactate Dehydrogenase Increased
6. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
7. Disseminated Intravascular Coagulation (systemic activation of blood coagulation)
8. Blood Creatine Phosphokinase Increased
9. Blood Bilirubin Increased
10. Gait Abnormal

Metromidol:

1. Balance Disorder
2. Fall
3. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving)
4. Extrapyramidal Disorder (involuntary muscle spasms in the face and neck)
5. Emotional Distress
6. Eating Disorder
7. Dysphagia (a condition in which swallowing is difficult or painful)
8. Dyslalia (inability to articulate comprehensible speech)
9. Dysgraphia (impaired ability to learn to write)
10. Drug Ineffective

Flecainide Acetate:

• not at all: 0 %
• somewhat: 13.24 %
• moderate: 22.06 %
• high: 42.65 %
• very high: 22.06 %

Clonidine Hydrochloride:

• not at all: 0 %
• somewhat: 16.67 %
• moderate: 44.44 %
• high: 16.67 %
• very high: 22.22 %

Metromidol:

• not at all: 6.67 %
• somewhat: 6.67 %
• moderate: 26.67 %
• high: 46.67 %
• very high: 13.33 %