Abilify and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abilify (aripiprazole) and Compazine (prochlorperazine maleate). Common drug interactions include suspiciousness among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Abilify and Compazine. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

On Jul, 09, 2026

79 people who take Abilify and Compazine together, and have interactions are studied.

Abilify and Compazine drug interactions.

What are the common drug interactions of Abilify and Compazine, by gender? *:

female:

Suspiciousness
Anaemia (lack of blood)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Dysphagia (a condition in which swallowing is difficult or painful)
Haematuria (presence of blood in urine)
Abscess (pus)
Allergy to chemicals
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)

male:

Fatigue (feeling of tiredness)
Chronic kidney disease
Lymphadenopathy (disease or enlargement of lymph nodes)
Nephrolithiasis (calculi in the kidneys)
Osteonecrosis (death of bone)
Pain
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
White blood cell count decreased
Dysuria (painful or difficult urination)
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)

What are the common drug interactions of Abilify and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abnormal behaviour
Device dislocation
Drug hypersensitivity
General physical health deterioration (weak health status)
Injury
Pain
Tardive dyskinesia (a disorder that involves involuntary movements)

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Bone density decreased
Bone loss
Chronic kidney disease
Emotional distress
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Femur fracture
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)

40-49:

Back pain
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal pain upper
Activities of daily living impaired
Adnexa uteri pain
Drug effect delayed
Hepatic pain (pain in liver)
Limb crushing injury (crushing injury of upper limb)

50-59:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest discomfort
Chest pain
Confusional state
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)

60+:

Fatigue (feeling of tiredness)
Infection
Abdominal distension
Asthenia (weakness)
Blood magnesium decreased
Carbohydrate antigen 125 increased
Chronic kidney disease
Contusion (a type of hematoma of tissue in which capillaries)
Death
Decreased appetite

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 20 people, 25.32%
Migraine (headache): 13 people, 16.46%
Pain: 12 people, 15.19%
Stress And Anxiety: 11 people, 13.92%
Insomnia (sleeplessness): 7 people, 8.86%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 8.86%
Headache (pain in head): 7 people, 8.86%
Multiple Myeloma (cancer of the plasma cells): 7 people, 8.86%
Joint Pain: 7 people, 8.86%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 7.59%

* Approximation only. Some reports may have incomplete information.

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