Abilify and Eszopiclone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abilify (aripiprazole) and Eszopiclone (eszopiclone). Common drug interactions include fall among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Abilify and Eszopiclone. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.

What is Eszopiclone?

Eszopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 4,258 Eszopiclone users. Check the latest studies of Eszopiclone.

On Jul, 08, 2026

84 people who take Abilify and Eszopiclone together, and have interactions are studied.

Abilify and Eszopiclone drug interactions.

What are the common drug interactions of Abilify and Eszopiclone, by gender? *:

female:

Fall
Glomerulonephritis chronic (long lasting group of conditions that affect parts of the kidneys called glomeruli)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal haematoma (blood collection in kidney)
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise)
Pneumonia
Antinuclear antibody positive
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

Anxiety
Drug ineffective
Blood pressure decreased
Coeliac artery stenosis (abnormal narrowing of coeliac artery)
Gingival swelling (gums swelling)
Pancreatitis acute (sudden inflammation of pancreas)
Psychotic disorder
Respiratory disorder (respiratory disease)
Thrombosis (formation of a blood clot inside a blood vessel)
Weight increased

What are the common drug interactions of Abilify and Eszopiclone, by age (0-1 to 60+)? *:

0-1:

Maternal exposure during pregnancy (use of substance during pregnancy)
Speech disorder developmental

2-9:

n/a

10-19:

n/a

20-29:

Colitis ulcerative (inflammation of colon with ulcer)
Restlessness (not able to rest)
Abortion (termination of pregnancy)
Death
Erythema multiforme (a type of hypersensitivity reaction)
Maternal exposure during pregnancy (use of substance during pregnancy)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

30-39:

Completed suicide (act of taking one's own life)
Psychiatric symptom
Maternal exposure during pregnancy (use of substance during pregnancy)
Altered state of consciousness (altered state of mind)
Antinuclear antibody positive
Arthralgia (joint pain)
Blepharospasm (any abnormal contraction or twitch of the eyelid)
Blood pressure increased
Cardiac failure
Cervical vertebral fracture

40-49:

Rash
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Cough
Emotional distress
Hypertension (high blood pressure)
Injury
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Weight increased
Acute sinusitis
Fatigue (feeling of tiredness)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Glomerulonephritis chronic (long lasting group of conditions that affect parts of the kidneys called glomeruli)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal haematoma (blood collection in kidney)
Groin abscess (pus in groin)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephritic syndrome (a collection of signs (known as a syndrome) associated with disorders affecting the kidneys, more specifically glomerular disorders)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal discomfort

60+:

Delusion (a false belief or opinion)
Dysphagia (a condition in which swallowing is difficult or painful)
Irritability
Salivary hypersecretion (excess saliva secretion)
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Dystonia (abnormal muscle tone)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Aphasia (damage to the parts of the brain that control language)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 13 people, 15.48%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 13.10%
Pain: 10 people, 11.90%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 11.90%
Bipolar Disorder (mood disorder): 9 people, 10.71%
Sleep Disorder: 8 people, 9.52%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 9.52%
Stress And Anxiety: 7 people, 8.33%
High Blood Cholesterol: 7 people, 8.33%
Drowsiness: 6 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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