Abilify and Exforge drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abilify (aripiprazole) and Exforge (amlodipine besylate; valsartan). Common drug interactions include cardiac failure among females and bruxism among males.

The phase IV clinical study analyzes what interactions people have when they take Abilify and Exforge. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,455 Abilify users. Check the latest studies of Abilify.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

On Aug, 05, 2026

45 people who take Abilify and Exforge together, and have interactions are studied.

What are the common drug interactions of Abilify and Exforge, by gender? *:

female:

Cardiac failure
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Urinary tract infection
Paresis (a condition of muscular weakness)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Monoparesis (one limb is very weak, but not completely paralyzed)
Diplegia (paralysis of corresponding parts on both sides of the body)
Fall
Confusional state
Nephrolithiasis (calculi in the kidneys)

male:

Bruxism (habitual grinding of the teeth, typically during sleep)
Pruritus (severe itching of the skin)
Asthenia (weakness)
Chronic kidney disease
Dehydration (dryness resulting from the removal of water)
Emotional distress
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pain

What are the common drug interactions of Abilify and Exforge, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug ineffective
Maternal exposure during pregnancy (use of substance during pregnancy)
Premature delivery
Premature rupture of membranes
Threatened labour (premature labour is the onset of labour between 24 and 37 weeks of pregnancy)

40-49:

n/a

50-59:

Bruxism (habitual grinding of the teeth, typically during sleep)
Pruritus (severe itching of the skin)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Arthralgia (joint pain)
Dyskinesia (abnormality or impairment of voluntary movement)
Eye irritation
Weight increased
Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

60+:

Cardiac failure
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Anxiety
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease
Confusional state
Emotional distress
Oxygen saturation decreased
Pain
Psychomotor skills impaired

What are the existing conditions these people have? *

High Blood Pressure: 21 people, 46.67%
Type 2 Diabetes: 15 people, 33.33%
High Blood Cholesterol: 12 people, 26.67%
Bipolar Disorder (mood disorder): 12 people, 26.67%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 15.56%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 11.11%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 11.11%
Psychotic Disorder: 3 people, 6.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.67%
Mania (a state of abnormally elevated or irritable mood): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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