Abilify and Mesalamine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abilify (aripiprazole) and Mesalamine (mesalamine). Common drug interactions include suicidal ideation among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Abilify and Mesalamine. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,456 Abilify users. Check the latest studies of Abilify.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

69 people who take Abilify and Mesalamine together, and have interactions are studied.

Abilify and Mesalamine drug interactions.

What are the common drug interactions of Abilify and Mesalamine, by gender? *:

female:

Suicidal ideation
Abdominal pain
Body temperature decreased
Heart rate decreased
Sedation
Accident
Affective disorder (mental disorder)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Cellulitis (infection under the skin)

male:

Abdominal discomfort
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematochezia (passage of stools containing blood)
Left ventricular failure (left ventricle fails to contract forcefully)
Ligament rupture (tear in ligament)
Lower limb fracture
Nephrolithiasis (calculi in the kidneys)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)

What are the common drug interactions of Abilify and Mesalamine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Road traffic accident

10-19:

Haematochezia (passage of stools containing blood)
Abdominal discomfort
Fall
Infusion related reaction
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

20-29:

Left ventricular failure (left ventricle fails to contract forcefully)
Decreased appetite
Frequent bowel movements
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Muscle twitching
Nausea (feeling of having an urge to vomit)
Pain in extremity
Proctalgia (pain in the rectum)
Rectal haemorrhage (bleeding from anus)
Testicular pain (pain in testes)

30-39:

Abdominal pain
Dysphonia (speech disorder attributable to a disorder of phonation)
Frequent bowel movements
Malaise (a feeling of general discomfort or uneasiness)
Rash
Respiratory disorder (respiratory disease)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Anxiety
Bone density decreased

40-49:

Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nausea (feeling of having an urge to vomit)
Pain
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Poisoning
Poor quality sleep
Social avoidant behaviour (avoiding social connection a personality disorder)
Stress
Suicide attempt
Synovial cyst (cyst of joint filled with synovial fluid)

50-59:

Urinary tract infection
Blood pressure fluctuation
Heart rate irregular
Arthralgia (joint pain)
Blood pressure increased
Body temperature decreased
Heart rate decreased
Pneumonia
Frequent bowel movements
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

60+:

Sedation
Influenza
Flatulence (flatus expelled through the anus)
Gastroenteritis (inflammation of stomach and intestine)
Influenza like illness
Nasopharyngitis (inflammation of the nasopharynx)
Pyrexia (fever)
Incision site infection (infection at incision site)
Staphylococcal infection (an infection with staphylococcus bacteria)
Suicidal ideation

What are the existing conditions these people have? *

Inflammation: 14 people, 20.29%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 13 people, 18.84%
Urinary Tract Infection: 10 people, 14.49%
Pain: 7 people, 10.14%
Sleep Apnea Syndrome: 6 people, 8.70%
Nausea (feeling of having an urge to vomit): 5 people, 7.25%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 5.80%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 5.80%
Drowsiness: 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

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