Abilify and Revatio drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abilify (aripiprazole) and Revatio (sildenafil citrate). Common drug interactions include catheter site pain among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Abilify and Revatio. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.

What is Revatio?

Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.



On Jul, 06, 2026

49 people who take Abilify and Revatio together, and have interactions are studied.

Abilify and Revatio drug interactions.

What are the common drug interactions of Abilify and Revatio, by gender? *:

female:

  1. Catheter site pain
  2. Catheter site swelling
  3. Cellulitis (infection under the skin)
  4. Depressed mood
  5. Device dislocation
  6. Discomfort
  7. Drug intolerance (drug sensitivity)
  8. Dyspepsia (indigestion)
  9. Epistaxis (bleed from the nose)
  10. Face oedema (swelling of face)

male:

  1. Abdominal discomfort
  2. Diarrhoea
  3. Decreased appetite
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  6. Drug ineffective
  7. Dyspnoea (difficult or laboured respiration)
  8. Dyspnoea exertional (breathlessness or shortness of breath)
  9. Dystonia (abnormal muscle tone)
  10. Fatigue (feeling of tiredness)

What are the common drug interactions of Abilify and Revatio, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Pain in jaw
  2. Swelling face
  3. Swollen tongue (swelling of tongue)
  4. Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
  5. Vitreous floaters (spots before the eyes)
  6. Abdominal distension
  7. Device related infection
  8. Disease progression
  9. Fluid retention (an abnormal accumulation of fluid in the blood)
  10. Localised oedema (fluid retention in a particular part of the body)

40-49:

  1. Blood glucose decreased
  2. Cardiac disorder
  3. Death
  4. Dyspnoea (difficult or laboured respiration)
  5. Haematochezia (passage of stools containing blood)
  6. Lethargy (tiredness)
  7. Oedema (fluid collection in tissue)
  8. Respiratory depression (respiration has a rate below 12 breaths)
  9. Respiratory failure (inadequate gas exchange by the respiratory system)

50-59:

  1. Nasopharyngitis (inflammation of the nasopharynx)
  2. Abdominal discomfort
  3. Myalgia (muscle pain)
  4. Nausea (feeling of having an urge to vomit)
  5. Sputum discoloured
  6. Fatigue (feeling of tiredness)
  7. Headache (pain in head)
  8. Bacteriuria (presence of bacteria in urine)
  9. Chest pain
  10. Contusion (a type of hematoma of tissue in which capillaries)

60+:

  1. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  2. Fluid retention (an abnormal accumulation of fluid in the blood)
  3. Dysphonia (speech disorder attributable to a disorder of phonation)
  4. Dyspnoea (difficult or laboured respiration)
  5. Fatigue (feeling of tiredness)
  6. Headache (pain in head)
  7. Muscular weakness (muscle weakness)
  8. Myalgia (muscle pain)
  9. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  10. Pain in jaw

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 33 people, 67.35%
  2. Urination - Excessive Volume: 4 people, 8.16%
  3. Joint Pain: 4 people, 8.16%
  4. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Abilify and Revatio:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Revatio:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Abilify and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Revatio and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on aripiprazole and sildenafil citrate (the active ingredients of Abilify and Revatio, respectively), and Abilify and Revatio (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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