Abilify and Zomig drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abilify (aripiprazole) and Zomig (zolmitriptan). Common drug interactions include convulsion among females and chronic hepatic failure among males.

The phase IV clinical study analyzes what interactions people have when they take Abilify and Zomig. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,456 Abilify users. Check the latest studies of Abilify.

What is Zomig?

Zomig has active ingredients of zolmitriptan. It is often used in migraine. eHealthMe is studying from 7,356 Zomig users. Check the latest studies of Zomig.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

67 people who take Abilify and Zomig together, and have interactions are studied.

What are the common drug interactions of Abilify and Zomig, by gender? *:

female:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diabetes mellitus inadequate control
Diabetic coma
Diabetic complication
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Neuropathy peripheral (surface nerve damage)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Tremor (trembling or shaking movements in one or more parts of your body)
Drug hypersensitivity
Gastric disorder (disease of stomach)

male:

Chronic hepatic failure (long lasting liver failure)
Death
Drug hypersensitivity

What are the common drug interactions of Abilify and Zomig, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Nausea (feeling of having an urge to vomit)
Presyncope
Tremor (trembling or shaking movements in one or more parts of your body)
Vertigo
Blood cholesterol increased
Blood triglycerides increased
Hyperlipidaemia (presence of excess lipids in the blood)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Obesity (having too much body fat)
Type 1 diabetes mellitus

30-39:

Blood cholesterol increased
Blood triglycerides increased
Hyperlipidaemia (presence of excess lipids in the blood)
Muscular weakness (muscle weakness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasopharyngitis (inflammation of the nasopharynx)
Night sweats (sweating in night)
Obesity (having too much body fat)
Pain
Suicidal ideation

40-49:

Neck pain
Oedema peripheral (superficial swelling)
Peroneal nerve palsy
Pseudolymphoma (group of disorders having a benign course but exhibiting clinical and histological features suggestive of malignant lymphoma)
Sensory loss (senses loss)
Skin exfoliation (removal of the oldest dead skin cells)
Speech disorder
Stress
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Temperature intolerance (inability to go in temperature)

50-59:

Avulsion fracture (bone fracture)
Bone disorder
Fall
Foot fracture
Mitral valve prolapse (heart's mitral valve doesn't work well)
Osteoporosis (bones weak and more likely to break)
Tibia fracture (fracture of lower leg bone)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug hypersensitivity
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)

60+:

Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)
Restlessness (not able to rest)
Stress
Abdominal pain
Abdominal tenderness
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 28.36%
Stress And Anxiety: 11 people, 16.42%
Bipolar Disorder (mood disorder): 10 people, 14.93%
Insomnia (sleeplessness): 9 people, 13.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 10.45%
Weight Decreased: 6 people, 8.96%
Sleep Disorder: 5 people, 7.46%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 7.46%
Nausea (feeling of having an urge to vomit): 4 people, 5.97%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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