Abraxane and Elavil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abraxane (paclitaxel) and Elavil (amitriptyline hydrochloride). Common drug interactions include oral candidiasis among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Abraxane and Elavil. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Abraxane?

Abraxane has active ingredients of paclitaxel. It is often used in breast cancer metastatic. eHealthMe is studying from 19,196 Abraxane users. Check the latest studies of Abraxane.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.

On Jul, 13, 2026

30 people who take Abraxane and Elavil together, and have interactions are studied.

What are the common drug interactions of Abraxane and Elavil, by gender? *:

female:

Oral candidiasis (fungal infection of mouth)
Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Pneumonia
Metastases to lung (cancer spreads to lung)
Abdominal pain
Abdominal sepsis (abdominal infection)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

male:

Asthenia (weakness)
Chest pain
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aortic disorder
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrophic vulvovaginitis (inflammation of the vulva)

What are the common drug interactions of Abraxane and Elavil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diarrhoea
Pain
Vomiting

50-59:

Diarrhoea haemorrhagic (bloody diarrhoea)
Dysgeusia (disorder of the sense of taste)
Macrophages increased (increased immune cells that eats foreign material and dead cells)
Metastases to skin (cancer spreads to skin)
Oral candidiasis (fungal infection of mouth)
Dental caries
Device related infection
Open wound
Tenderness (pain or discomfort when an affected area is touched)
Tooth extraction

60+:

Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
Keratitis (eye's cornea, the front part of the eye, becomes inflamed)
Corneal oedema (corneal swelling)
Disease progression
Myalgia (muscle pain)
Pain
Streptococcal infection
Aspartate aminotransferase increased
Blood bilirubin increased
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Pain: 2 people, 6.67%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 6.67%
Breast Cancer Female: 2 people, 6.67%
Breast Cancer: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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