Abraxane and Promethazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abraxane (paclitaxel) and Promethazine (promethazine hydrochloride). Common drug interactions include aortic arteriosclerosis among females and syncope among males.

The phase IV clinical study analyzes what interactions people have when they take Abraxane and Promethazine. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Abraxane?

Abraxane has active ingredients of paclitaxel. It is often used in breast cancer metastatic. eHealthMe is studying from 19,196 Abraxane users. Check the latest studies of Abraxane.

What is Promethazine?

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.

On Jul, 12, 2026

58 people who take Abraxane and Promethazine together, and have interactions are studied.

Abraxane and Promethazine drug interactions.

What are the common drug interactions of Abraxane and Promethazine, by gender? *:

female:

Aortic arteriosclerosis (hardening of the aortic arteries)
Arthralgia (joint pain)
Band neutrophil count increased
Blood glucose decreased
Blood glucose increased
Blood triglycerides increased
Blood urea nitrogen/creatinine ratio increased
Blood urine present
Body temperature fluctuation
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)

male:

Syncope (loss of consciousness with an inability to maintain postural tone)
Dehydration (dryness resulting from the removal of water)
Feeding disorder (when children refuse to eat certain food groups)
Hypoxia (low oxygen in tissues)
Malignant neoplasm progression (cancer tumour came back)
Memory impairment
Mucosal inflammation (infection of mucous membrane)
Pain
Pleural effusion (water on the lungs)
Pneumonia

What are the common drug interactions of Abraxane and Promethazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyskinesia (abnormality or impairment of voluntary movement)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Dystonia (abnormal muscle tone)
Emotional disorder
Emotional distress
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Family stress
Fatigue (feeling of tiredness)

50-59:

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Febrile neutropenia (fever with reduced white blood cells)
Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Leukopenia (less number of white blood cells in blood)
Pain
Sepsis (a severe blood infection that can lead to organ failure and death)
Skin lesion
Device related infection
Hyperglycaemia (high blood sugar)

60+:

Syncope (loss of consciousness with an inability to maintain postural tone)
Weight decreased
Urinary tract infection
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Infusion site swelling
Bacterial sepsis
Confusional state
Cough
Feeding disorder (when children refuse to eat certain food groups)
Hypoxia (low oxygen in tissues)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 18.97%
High Blood Pressure: 10 people, 17.24%
Constipation: 8 people, 13.79%
Pancreatic Carcinoma (pancreatic cancer): 8 people, 13.79%
Pain: 8 people, 13.79%
Immunodeficiency Common Variable: 7 people, 12.07%
Diarrhea: 7 people, 12.07%
Non-Small Cell Lung Cancer Stage Iv: 7 people, 12.07%
Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 8.62%
Breast Cancer Female: 5 people, 8.62%

* Approximation only. Some reports may have incomplete information.

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