Abraxane and Unasyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abraxane (paclitaxel) and Unasyn (ampicillin sodium; sulbactam sodium). Common drug interactions include dry mouth among females and duodenal perforation among males.

The phase IV clinical study analyzes what interactions people have when they take Abraxane and Unasyn. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Abraxane?

Abraxane has active ingredients of paclitaxel. It is often used in breast cancer metastatic. eHealthMe is studying from 19,196 Abraxane users. Check the latest studies of Abraxane.

What is Unasyn?

Unasyn has active ingredients of ampicillin sodium; sulbactam sodium. eHealthMe is studying from 4,474 Unasyn users. Check the latest studies of Unasyn.

On Jul, 15, 2026

34 people who take Abraxane and Unasyn together, and have interactions are studied.

What are the common drug interactions of Abraxane and Unasyn, by gender? *:

female:

Dry mouth
Epistaxis (bleed from the nose)
Foot deformity (functional disability of foot)
Foot fracture
Gingival erosion (gum ulcer)
Bone disorder
Atelectasis (partial or complete collapse of the lung)
Anxiety
Osteonecrosis of jaw (death of bone of jaw)
Metastases to bone (cancer spreads to bone)

male:

Duodenal perforation (complication of duodenal ulcer)
Muscular weakness (muscle weakness)
Pulmonary oedema (fluid accumulation in the lungs)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Dyspnoea (difficult or laboured respiration)
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Lung infection
Non-cardiac chest pain
Oedema peripheral (superficial swelling)

What are the common drug interactions of Abraxane and Unasyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal hernia
Alopecia (absence of hair from areas of the body)
Anxiety
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Body temperature decreased
Bone disorder
Cellulitis (infection under the skin)
Chest pain
Chills (felling of cold)

40-49:

Abdominal pain
Arthralgia (joint pain)
Benign neoplasm of thyroid gland (benign (non-cancerous) tumours of the thyroid gland)
Bone disorder
Colon neoplasm (cancer from uncontrolled cell growth in the colon or rectum)
Decreased interest
Defaecation urgency (a sudden compelling urge to defecate)
Depression
Dysfunctional uterine bleeding
Dyspnoea (difficult or laboured respiration)

50-59:

Ascites (accumulation of fluid in the abdominal cavity)
Atelectasis (partial or complete collapse of the lung)
Blood alkaline phosphatase increased
Bone disorder
Bone pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac murmur (an heart sound in valve abnormality)
Carotid artery disease
Carotid body tumour (cancer of carotid artery)
Constipation

60+:

Oedema peripheral (superficial swelling)
Atelectasis (partial or complete collapse of the lung)
Pneumonia
Osteonecrosis of jaw (death of bone of jaw)
Back pain
Blindness unilateral
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Candidiasis (candidiasis or thrush is a fungal infection)
Cardiomegaly (increased size of heart than normal)
Cellulitis (infection under the skin)

What are the existing conditions these people have? *

Breast Cancer: 13 people, 38.24%
Metastases To Bone (cancer spreads to bone): 8 people, 23.53%
Lung Cancer - Non-Small Cell (lung cancer): 4 people, 11.76%
Diabetes: 3 people, 8.82%
Non-Small Cell Lung Cancer Recurrent (type of epithelial lung cancer reoccurrence): 2 people, 5.88%
Constipation: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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