Accolate and Bumex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Accolate (zafirlukast) and Bumex (bumetanide). Common drug interactions include sinusitis among females and blindness among males.

The phase IV clinical study analyzes what interactions people have when they take Accolate and Bumex. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Accolate?

Accolate has active ingredients of zafirlukast. It is often used in asthma. eHealthMe is studying from 4,220 Accolate users. Check the latest studies of Accolate.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.



On Jul, 11, 2026

25 people who take Accolate and Bumex together, and have interactions are studied.

Accolate and Bumex drug interactions.

What are the common drug interactions of Accolate and Bumex, by gender? *:

female:

  1. Sinusitis (inflammation of sinus)
  2. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  3. Dyspnoea (difficult or laboured respiration)
  4. Fatigue (feeling of tiredness)
  5. Blood pressure decreased
  6. Erythema (redness of the skin)
  7. Eschar (dead tissue that falls off (sheds) from healthy skin)
  8. Generalised oedema (swelling all over the body)
  9. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  10. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

male:

  1. Blindness
  2. Blood glucose increased
  3. Upper respiratory tract infection
  4. Vasculitis (inflammation of a blood vessel or blood vessels)
  5. Cardiac disorder
  6. Churg strauss syndrome (infection of small arteries and vein)
  7. Dyspnoea (difficult or laboured respiration)
  8. Hypoglycaemic seizure (low blood sugar)
  9. Joint dislocation (a joint position is changed from normal position)
  10. Lung function decreased

What are the common drug interactions of Accolate and Bumex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Weakness
  2. Blood pressure decreased
  3. Dyspnoea (difficult or laboured respiration)
  4. Erythema (redness of the skin)
  5. Eschar (dead tissue that falls off (sheds) from healthy skin)
  6. Fatigue (feeling of tiredness)
  7. Generalised oedema (swelling all over the body)
  8. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  9. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  10. Pruritus (severe itching of the skin)

50-59:

  1. Sinusitis (inflammation of sinus)
  2. Blindness
  3. Blood glucose increased
  4. Calcinosis (calcium deposits in any soft tissue)
  5. Cardiac disorder
  6. Churg strauss syndrome (infection of small arteries and vein)
  7. Cough
  8. Diabetes mellitus inadequate control
  9. Diabetic ulcer
  10. Drug dependence

60+:

  1. Asthenia (weakness)
  2. Confusion
  3. Clostridium difficile sepsis (infection(pus formation) of colon by clostridium difficile bacteria)
  4. Constipation
  5. Cough
  6. Decreased appetite
  7. Dehydration (dryness resulting from the removal of water)
  8. Dizziness
  9. Dry mouth
  10. Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 6 people, 24.00%
  2. Pain: 6 people, 24.00%
  3. Migraine (headache): 5 people, 20.00%
  4. Stress And Anxiety: 2 people, 8.00%
  5. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 8.00%
  6. Irritable Bowel Syndrome: 2 people, 8.00%
  7. Hypersensitivity: 2 people, 8.00%
  8. High Blood Pressure: 2 people, 8.00%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Accolate and Bumex?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Accolate and Bumex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Accolate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bumex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Accolate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bumex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on zafirlukast and bumetanide (the active ingredients of Accolate and Bumex, respectively), and Accolate and Bumex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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