Accolate and Vanceril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Accolate (zafirlukast) and Vanceril (beclomethasone dipropionate). Common drug interactions include intervertebral disc herniation among females and sweating increased among males.

The phase IV clinical study analyzes what interactions people have when they take Accolate and Vanceril. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Accolate?

Accolate has active ingredients of zafirlukast. It is often used in asthma. eHealthMe is studying from 4,220 Accolate users. Check the latest studies of Accolate.

What is Vanceril?

Vanceril has active ingredients of beclomethasone dipropionate. eHealthMe is studying from 1,502 Vanceril users. Check the latest studies of Vanceril.



On Jul, 11, 2026

74 people who take Accolate and Vanceril together, and have interactions are studied.

Accolate and Vanceril drug interactions.

What are the common drug interactions of Accolate and Vanceril, by gender? *:

female:

  1. Intervertebral disc herniation (spinal disc herniation)
  2. Mononeuritis (single nerve damage)
  3. Peripheral neuropathy (damage to nerves of the peripheral nervous system)
  4. Pruritus (severe itching of the skin)
  5. Weight increased
  6. Arrhythmia (irregular heartbeat)
  7. Blood pressure increased
  8. Cushingoid (obesity and weakening of the muscles)
  9. Drug effect decreased
  10. Gastritis (inflammation of stomach)

male:

  1. Sweating increased (excess sweating)
  2. Acute respiratory failure
  3. Pleuritic pain
  4. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  5. Atrioventricular block (heart block)
  6. Benign intracranial hypertension (benign intracranial hypertension (bih) is a headache syndrome)
  7. Blood carbon dioxide increased
  8. Blood ph decreased
  9. Constipation
  10. Cough

What are the common drug interactions of Accolate and Vanceril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Benign intracranial hypertension (benign intracranial hypertension (bih) is a headache syndrome)
  2. Headache (pain in head)
  3. Insulin resistance
  4. Papilloedema (optic disc swelling)
  5. Vomiting
  6. Abdominal pain
  7. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  8. Henoch-schonlein purpura (inflammation of the blood vessels in the skin and other body organs)
  9. Hyperglycaemia (high blood sugar)
  10. Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)

20-29:

  1. Arrhythmia (irregular heartbeat)
  2. Cardiac arrest
  3. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  4. Drug ineffective
  5. Status asthmaticus (a asthma attack not responds to regular medicines)
  6. Vomiting
  7. Acute respiratory failure
  8. Breath sounds decreased
  9. Cough
  10. Pulmonary congestion (congestion in the lungs)

30-39:

  1. Syncope (loss of consciousness with an inability to maintain postural tone)
  2. Anaphylactic reaction (serious allergic reaction)
  3. Cyst (a closed sac)
  4. Dyspnoea (difficult or laboured respiration)
  5. Hypoglycaemia (deficiency of glucose in the bloodstream)
  6. Injection site urticaria (rash of round, red welts on the skin at injection site)
  7. Umbilical cord vascular disorder
  8. Accommodation disorder
  9. Cerebral cyst (fluid filled tumour of brain)
  10. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

40-49:

  1. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  2. Back pain
  3. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  4. Chest pain
  5. Crying
  6. Depression
  7. Drug effect decreased
  8. Halitosis (offensive breath)
  9. Headache (pain in head)
  10. Hyperglycaemia (high blood sugar)

50-59:

  1. Blood pressure increased
  2. Chronic obstructive airways disease
  3. Dyspnoea (difficult or laboured respiration)
  4. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  5. Epistaxis (bleed from the nose)
  6. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  7. Haemorrhage subcutaneous (bleeding from skin)
  8. Nausea (feeling of having an urge to vomit)
  9. Pleuritic pain
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

  1. Churg strauss syndrome (infection of small arteries and vein)
  2. Dyspnoea (difficult or laboured respiration)
  3. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  4. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  5. Constipation
  6. Diplopia (double vision)
  7. Faecal impaction
  8. Guillain barre syndrome (the body's immune system attacks its peripheral nervous system)
  9. Haemoglobin decreased
  10. Hypoaesthesia (reduced sense of touch or sensation)

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Accolate and Vanceril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Accolate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vanceril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Accolate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vanceril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on zafirlukast and beclomethasone dipropionate (the active ingredients of Accolate and Vanceril, respectively), and Accolate and Vanceril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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