Accupril and Accutane drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Accupril (quinapril hydrochloride) and Accutane (isotretinoin). Common drug interactions include fatigue among females and colitis ulcerative among males.
The phase IV clinical study analyzes what interactions people have when they take Accupril and Accutane. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.
What is Accupril?
Accupril has active ingredients of quinapril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,404 Accupril users. Check the latest studies of Accupril.
What is Accutane?
Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 35,221 Accutane users. Check the latest studies of Accutane.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
31 people who take Accupril and Accutane together, and have interactions are studied.

What are the common drug interactions of Accupril and Accutane, by gender? *:
female:
- Fatigue (feeling of tiredness)
- Antinuclear factor positive
- Arthralgia (joint pain)
- Blood cholesterol increased
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Joint swelling
- Myalgia (muscle pain)
- Pleurisy (inflammation of the pleurae, which causes pain when breathing)
- Sore throat (pain or irritation of the throat)
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
male:
- Colitis ulcerative (inflammation of colon with ulcer)
- Inflammatory bowel disease
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
- Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
- Pouchitis (inflammatory bowel disease)
- Hamartoma (non-cancerous tumour)
- Pseudopolyp (projecting masses of scar tissue that develop from granulation tissue during the healing phase in repeated cycle of ulceration)
- Pelvic abscess
- Dry mouth
- Lip dry
What are the common drug interactions of Accupril and Accutane, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Colitis (inflammation of colon)
- Colitis ulcerative (inflammation of colon with ulcer)
- Colonic polyp (extra part of colon tissue grow in intestine)
- Feeling of despair
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Headache (pain in head)
- Inflammatory bowel disease
- Irritable bowel syndrome
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Haematochezia (passage of stools containing blood)
30-39:
n/a
40-49:
- Fatigue (feeling of tiredness)
- Joint swelling
- Lung disorder (lung disease)
- Myalgia (muscle pain)
- Pleurisy (inflammation of the pleurae, which causes pain when breathing)
- Sore throat (pain or irritation of the throat)
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
- Cellulitis (infection under the skin)
- Chest pain
- Drug induced lupus erythematosus (an autoimmune disorder brought on by a reaction to medication)
50-59:
- Appetite increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires)
- Fatigue (feeling of tiredness)
- Lip dry
- Migraine (headache)
- Weight increased
60+:
n/a
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Accupril and Accutane:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Accupril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Accutane:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Accupril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Accutane and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on quinapril hydrochloride and isotretinoin (the active ingredients of Accupril and Accutane, respectively), and Accupril and Accutane (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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