Accuretic and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Accuretic (hydrochlorothiazide; quinapril hydrochloride) and Seroquel (quetiapine fumarate). Common drug interactions include essential hypertension among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Accuretic and Seroquel. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Accuretic?

Accuretic has active ingredients of hydrochlorothiazide; quinapril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 1,106 Accuretic users. Check the latest studies of Accuretic.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.



On Aug, 13, 2026

20 people who take Accuretic and Seroquel together, and have interactions are studied.

Accuretic and Seroquel drug interactions.

What are the common drug interactions of Accuretic and Seroquel, by gender? *:

female:

  1. Essential hypertension (primary hypertension)
  2. Diarrhoea
  3. Arthralgia (joint pain)
  4. Back pain
  5. Ear pain
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Oropharyngeal pain
  8. Pain in extremity
  9. Tooth abscess (pus formation in tooth)
  10. Upper respiratory tract infection

male:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  3. Neuropathy peripheral (surface nerve damage)
  4. Pancreatitis (inflammation of pancreas)
  5. Type 2 diabetes mellitus
  6. Arrhythmia (irregular heartbeat)
  7. Diabetic nephropathy (diabetic kidney disease)
  8. Glycosuria (excretion of glucose into the urine)
  9. Haematemesis (vomiting of blood)
  10. Joint swelling

What are the common drug interactions of Accuretic and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Arrhythmia (irregular heartbeat)
  2. Blood potassium decreased
  3. Diabetic nephropathy (diabetic kidney disease)
  4. Glycosuria (excretion of glucose into the urine)
  5. Haematemesis (vomiting of blood)
  6. Joint swelling
  7. Labyrinthitis (inflammation of the labyrinth or inner ear)
  8. Proteinuria (presence of protein in the urine)
  9. Renal failure (kidney dysfunction)
  10. Vision blurred

40-49:

  1. Anxiety disorder
  2. Arthralgia (joint pain)
  3. Back pain
  4. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
  5. Blood cholesterol increased
  6. Chest pain
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Constipation
  9. Diabetes mellitus inadequate control
  10. Essential hypertension (primary hypertension)

50-59:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Lower limb fracture
  3. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  4. Type 2 diabetes mellitus
  5. Syncope (loss of consciousness with an inability to maintain postural tone)

60+:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Nausea (feeling of having an urge to vomit)
  3. Anal sphincter atony (anal muscles are weak and cannot ensure an efficient sealing, this is called a sphincter atony)
  4. Aphagia (inability or refusal to swallow)
  5. Blood magnesium decreased
  6. Blood potassium decreased
  7. Cataract (clouding of the lens inside the eye)
  8. Constipation
  9. Decreased appetite
  10. Dizziness postural

What are the existing conditions these people have? *

  1. Asthma: 6 people, 30.00%
  2. Depression: 4 people, 20.00%
  3. Stress And Anxiety: 3 people, 15.00%
  4. Social Phobia (fear to go in social): 3 people, 15.00%
  5. Blood Pressure Abnormal: 3 people, 15.00%
  6. Cardiac Disorder: 3 people, 15.00%
  7. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 3 people, 15.00%
  8. Headache (pain in head): 3 people, 15.00%
  9. High Blood Cholesterol: 3 people, 15.00%
  10. Micturition Disorder (disease of passing urine): 3 people, 15.00%

* Approximation only. Some reports may have incomplete information.

Do you take Accuretic and Seroquel?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Accuretic and Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Accuretic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Accuretic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Seroquel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; quinapril hydrochloride and quetiapine fumarate (the active ingredients of Accuretic and Seroquel, respectively), and Accuretic and Seroquel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: