Accutane and Heparin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Accutane (isotretinoin) and Heparin (heparin sodium). Common drug interactions include drug hypersensitivity among females and inflammatory bowel disease among males.

The phase IV clinical study analyzes what interactions people have when they take Accutane and Heparin. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Accutane?

Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 35,221 Accutane users. Check the latest studies of Accutane.

What is Heparin?

Heparin has active ingredients of heparin sodium. It is often used in blood clots. eHealthMe is studying from 92,141 Heparin users. Check the latest studies of Heparin.

On Jul, 20, 2026

15 people who take Accutane and Heparin together, and have interactions are studied.

What are the common drug interactions of Accutane and Heparin, by gender? *:

female:

Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Haematochezia (passage of stools containing blood)
Hypotension (abnormally low blood pressure)
Internal injury
Intestinal haemorrhage (bleeding from intestine)
Libido decreased (loss of interest in sex)
Nausea (feeling of having an urge to vomit)

male:

Inflammatory bowel disease
Colitis ulcerative (inflammation of colon with ulcer)
Blood triglycerides increased
Dry skin
Intestinal haemorrhage (bleeding from intestine)
Asthenia (weakness)
Myalgia (muscle pain)
Oropharyngeal pain
Pyrexia (fever)
Death

What are the common drug interactions of Accutane and Heparin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Blood bilirubin increased
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Inflammatory bowel disease
Intestinal perforation (complete penetration of the wall of the intestine)
Sudden death

30-39:

Cardiac arrest
Infusion related reaction

40-49:

Pyrexia (fever)
Blood triglycerides increased
Colitis ulcerative (inflammation of colon with ulcer)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Depression
Dry skin
Duodenal ulcer
Epistaxis (bleed from the nose)
Gastrointestinal injury (injury to gastrointestinal tract)
Inflammatory bowel disease

50-59:

n/a

60+:

Colitis ulcerative (inflammation of colon with ulcer)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Anxiety
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cholangitis sclerosing (infection and obstruction of bile duct)
Disease recurrence
Dysarthria (speech disorder)
Emotional distress

What are the existing conditions these people have? *

Brain Neoplasm Malignant (brain cancer tumour): 3 people, 20.00%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 2 people, 13.33%
Pneumonia: 1 person, 6.67%
Metastases To Bone (cancer spreads to bone): 1 person, 6.67%
Malignant Neoplasm Of Islets Of Langerhans (cancer tumour of pancreas): 1 person, 6.67%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%
Heart Attack: 1 person, 6.67%
Gastric Cancer (stomach cancer): 1 person, 6.67%
Diabetes: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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