Aceon and Protonix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aceon (perindopril erbumine) and Protonix (pantoprazole sodium). Common drug interactions include paraesthesia among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Aceon and Protonix. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Aceon?

Aceon has active ingredients of perindopril erbumine. It is often used in high blood pressure. eHealthMe is studying from 1,785 Aceon users. Check the latest studies of Aceon.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.

On Jul, 21, 2026

35 people who take Aceon and Protonix together, and have interactions are studied.

What are the common drug interactions of Aceon and Protonix, by gender? *:

female:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Suicidal ideation
Vomiting
Abdominal pain upper
Acute sinusitis
Agitation (state of anxiety or nervous excitement)
Arthropathy
Asthma
Back pain
Blindness transient (sudden loss of vision)

male:

Asthenia (weakness)
Generalised oedema (swelling all over the body)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Neurodermatitis (a skin disorder characterized by long lasting itching and scratching)
Oedema peripheral (superficial swelling)
Pain in extremity
Pruritus (severe itching of the skin)
Skin exfoliation (removal of the oldest dead skin cells)
Skin lesion
Swelling face

What are the common drug interactions of Aceon and Protonix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Acute sinusitis
Agitation (state of anxiety or nervous excitement)
Anxiety
Arthropathy
Asthma
Back pain
Chest pain
Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
Confusional state

30-39:

n/a

40-49:

Neurodermatitis (a skin disorder characterized by long lasting itching and scratching)
Oedema peripheral (superficial swelling)
Pain in extremity
Pruritus (severe itching of the skin)
Skin exfoliation (removal of the oldest dead skin cells)
Skin lesion
Skin ulcer
Swelling face
Rash vesicular (rash with a small bubble)
Scab (a hard coating on the skin formed during the wound healing)

50-59:

Asthenia (weakness)
Calciphylaxis (is a syndrome with vascular calcium accumulation)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Generalised oedema (swelling all over the body)
Intervertebral disc disorder (spinal disc disorder)
Lower limb fracture
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pericardial effusion (fluid around the heart)
Pneumonia
Skin ulcer

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Fatigue (feeling of tiredness)
Headache (pain in head)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Nephrogenic anaemia (anaemia due to kidney disease)
Anaemia (lack of blood)
Anxiety
Blindness transient (sudden loss of vision)

What are the existing conditions these people have? *

High Blood Cholesterol: 8 people, 22.86%
Nuclear Magnetic Resonance Imaging Brain: 8 people, 22.86%
Diabetes: 8 people, 22.86%
Stable Angina (a constant chest pain): 4 people, 11.43%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 11.43%
Balance Disorder: 4 people, 11.43%
Cardiac Failure Congestive: 4 people, 11.43%
Gastric Disorder (disease of stomach): 4 people, 11.43%
Indigestion: 4 people, 11.43%
Muscle Spasms (muscle contraction): 4 people, 11.43%

* Approximation only. Some reports may have incomplete information.

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