Acetazolamide and Cefotaxime drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acetazolamide (acetazolamide) and Cefotaxime (cefotaxime sodium). Common drug interactions include pyrexia among females and toxic epidermal necrolysis among males.

The phase IV clinical study analyzes what interactions people have when they take Acetazolamide and Cefotaxime. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Acetazolamide?

Acetazolamide has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 6,178 Acetazolamide users. Check the latest studies of Acetazolamide.

What is Cefotaxime?

Cefotaxime has active ingredients of cefotaxime sodium. eHealthMe is studying from 7,559 Cefotaxime users. Check the latest studies of Cefotaxime.



On Aug, 04, 2026

48 people who take Acetazolamide and Cefotaxime together, and have interactions are studied.

Acetazolamide and Cefotaxime drug interactions.

What are the common drug interactions of Acetazolamide and Cefotaxime, by gender? *:

female:

  1. Pyrexia (fever)
  2. Blood lactate dehydrogenase increased
  3. Drug hypersensitivity
  4. Duodenal ulcer
  5. Haematuria present (presence of blood in urine due to trauma)
  6. Nausea (feeling of having an urge to vomit)
  7. Renal disorder (kidney disease)
  8. Rigors (an episode of shaking or exaggerated shivering)
  9. Blood urea increased
  10. Erythema (redness of the skin)

male:

  1. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  2. Hepatocellular injury (liver injury)
  3. Drug ineffective
  4. Cardiac arrest
  5. Cardiac failure congestive
  6. Cirrhosis alcoholic (chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue caused by alcoholism)
  7. Delirium tremens (a psychotic condition typical of withdrawal in chronic alcoholics)
  8. Drug level increased
  9. Hepatitis acute
  10. Pneumonia

What are the common drug interactions of Acetazolamide and Cefotaxime, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Altered state of consciousness (altered state of mind)
  2. Hydrocephalus (water on the brain)
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Subdural haematoma (blood collects between the skull and the surface of the brain)
  5. Drug ineffective

10-19:

n/a

20-29:

  1. Hepatocellular injury (liver injury)
  2. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  3. Liver injury
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Vomiting
  6. Drug level increased
  7. Hepatitis acute

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  2. Pyrexia (fever)
  3. Cardiac arrest
  4. Erythema (redness of the skin)
  5. Gastric ulcer perforation (stomach hole due to ulcer)
  6. Pruritus (severe itching of the skin)
  7. Acidosis (build-up of carbon dioxide in the blood)
  8. Blood creatine phosphokinase increased
  9. Bradycardia (abnormally slow heart action)
  10. Cardiac failure

What are the existing conditions these people have? *

  1. Sedation: 23 people, 47.92%
  2. Pneumonia: 23 people, 47.92%
  3. Diarrhea: 23 people, 47.92%
  4. Constipation: 23 people, 47.92%
  5. Stress And Anxiety: 22 people, 45.83%
  6. High Blood Pressure: 22 people, 45.83%
  7. Fever: 22 people, 45.83%
  8. Depression: 22 people, 45.83%
  9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 22 people, 45.83%
  10. Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 22 people, 45.83%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acetazolamide and Cefotaxime:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acetazolamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cefotaxime:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acetazolamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefotaxime and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acetazolamide and cefotaxime sodium (the active ingredients of Acetazolamide and Cefotaxime, respectively), and Acetazolamide and Cefotaxime (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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