Acetazolamide and Gilenya drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Acetazolamide (acetazolamide) and Gilenya (fingolimod). Common drug interactions include dyspnoea among females and depression among males.
The phase IV clinical study analyzes what interactions people have when they take Acetazolamide and Gilenya. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Acetazolamide?
Acetazolamide has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 6,178 Acetazolamide users. Check the latest studies of Acetazolamide.
What is Gilenya?
Gilenya has active ingredients of fingolimod. It is often used in multiple sclerosis. eHealthMe is studying from 111,893 Gilenya users. Check the latest studies of Gilenya.
22 people who take Acetazolamide and Gilenya together, and have interactions are studied.

What are the common drug interactions of Acetazolamide and Gilenya, by gender? *:
female:
- Dyspnoea (difficult or laboured respiration)
- Furuncle (infection of the hair follicle)
- Gastric disorder (disease of stomach)
- Heart rate increased
- Herpes zoster
- Meningitis cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
- Rash
- Spinal pain (pain in spine)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Headache (pain in head)
male:
- Depression
- Fatigue (feeling of tiredness)
- Ataxia (loss of full control of bodily movements)
- Blood glucose increased
- Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
- Choking (mechanical obstruction of the flow of air from the environment into the lungs)
- Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
- Dysarthria (speech disorder)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Gait disturbance
What are the common drug interactions of Acetazolamide and Gilenya, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
- Blindness unilateral
- Bradycardia (abnormally slow heart action)
- C-reactive protein increased
- Diplopia (double vision)
- Endocrine ophthalmopathy (increased water content of retroocular orbital tissues; associated with thyroid disease, usually hyperthyroidism)
- Fatigue (feeling of tiredness)
- Feeling hot
- Fungal infection
- Headache (pain in head)
40-49:
- Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
- Dysarthria (speech disorder)
- Aphasia (damage to the parts of the brain that control language)
- Asthenia (weakness)
- Csf pressure increased
- Diplopia (double vision)
- Eye movement disorder
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Hallucination, visual (seeing things that aren't there)
- Headache (pain in head)
50-59:
- Aphasia (damage to the parts of the brain that control language)
- Blood pressure increased
- Nausea (feeling of having an urge to vomit)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Stress
- Vomiting
- Balance disorder
- Gait disturbance
- Gastroenteritis (inflammation of stomach and intestine)
60+:
n/a
What are the existing conditions these people have? *
- Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 18.18%
- Flatulence (flatus expelled through the anus): 4 people, 18.18%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 18.18%
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 13.64%
- Quit Smoking: 2 people, 9.09%
- Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 9.09%
- Diabetes: 2 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Acetazolamide and Gilenya?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Acetazolamide (6,178 reports)
- Gilenya (111,893 reports)
Browse all drug interactions of Acetazolamide and Gilenya:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Acetazolamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Gilenya:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acetazolamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gilenya and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
- Alroughani R, "Fingolimod-associated amenorrhea: a report of three cases", Multiple Sclerosis Journal, 2014 Jan .
- Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .
- Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
- Alroughani R, "Fingolimod-associated amenorrhea: a report of three cases", Multiple Sclerosis Journal, 2014 Jan .
- Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on acetazolamide and fingolimod (the active ingredients of Acetazolamide and Gilenya, respectively), and Acetazolamide and Gilenya (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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