Acetazolamide and Paxil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Acetazolamide (acetazolamide) and Paxil (paroxetine hydrochloride). Common drug interactions include nausea among females and acute respiratory failure among males.
The phase IV clinical study analyzes what interactions people have when they take Acetazolamide and Paxil. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Acetazolamide?
Acetazolamide has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 6,178 Acetazolamide users. Check the latest studies of Acetazolamide.
What is Paxil?
Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.
23 people who take Acetazolamide and Paxil together, and have interactions are studied.

What are the common drug interactions of Acetazolamide and Paxil, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Vomiting
- Anaemia (lack of blood)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Dyspnoea (difficult or laboured respiration)
- Acidosis (build-up of carbon dioxide in the blood)
- Bacteraemia (presence of bacteria in the blood)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac valve disease (heart valve disease)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
male:
- Acute respiratory failure
- Depression suicidal (suicide depressive disorder)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
- Suicide attempt
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Chronic kidney disease
- Drug maladministration
- Face oedema (swelling of face)
- Nephrogenic anaemia (anaemia due to kidney disease)
What are the common drug interactions of Acetazolamide and Paxil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Dizziness
- Injury
- Migraine (headache)
- Nausea (feeling of having an urge to vomit)
- Pain
- Papilloedema (optic disc swelling)
- Tinnitus (a ringing in the ears)
- Vision blurred
- Visual impairment
30-39:
- Cerebral haemorrhage (bleeding within the brain)
- Csf pressure increased
- Disease progression
- Injury
- Migraine (headache)
- Nausea (feeling of having an urge to vomit)
- Pain
- Papilloedema (optic disc swelling)
- Vision blurred
- Visual impairment
40-49:
- Chest pain
- Dysarthria (speech disorder)
- Heart rate increased
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
- Thrombin-antithrombin iii complex increased
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Palpitations (feelings or sensations that your heart is pounding or racing)
50-59:
- Acute respiratory failure
- Depression suicidal (suicide depressive disorder)
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
- Suicide attempt
- Abscess limb (limb infection)
- Erythema (redness of the skin)
- Groin abscess (pus in groin)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Septic shock (shock due to blood infection)
- Urinary tract infection
60+:
- Anaemia (lack of blood)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Gangrene (body tissue dies)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Haemodynamic instability (disturbances in the blood movement in our body)
- Heparin-induced thrombocytopenia
- Hypotension (abnormally low blood pressure)
What are the existing conditions these people have? *
- Weakness: 3 people, 13.04%
- Serratia Sepsis (a bacterial whole body inflammation): 3 people, 13.04%
- Pain: 3 people, 13.04%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 13.04%
- High Blood Cholesterol: 3 people, 13.04%
- Erection Problems: 3 people, 13.04%
- Affective Disorder (mental disorder): 3 people, 13.04%
- Weight Decreased: 2 people, 8.70%
- Type 2 Diabetes: 2 people, 8.70%
- Nausea And Vomiting: 2 people, 8.70%
* Approximation only. Some reports may have incomplete information.
Do you take Acetazolamide and Paxil?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Acetazolamide (6,178 reports)
- Paxil (92,546 reports)
Browse all drug interactions of Acetazolamide and Paxil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Acetazolamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Paxil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acetazolamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Paxil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on acetazolamide and paroxetine hydrochloride (the active ingredients of Acetazolamide and Paxil, respectively), and Acetazolamide and Paxil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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