Acetylsalicylic acid and Definity drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acetylsalicylic acid (aspirin) and Definity (perflutren). Common drug interactions include anxiety among females and anaphylactic reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Acetylsalicylic acid and Definity. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Acetylsalicylic acid?

Acetylsalicylic acid has active ingredients of aspirin. It is often used in high blood pressure. eHealthMe is studying from 119,766 Acetylsalicylic acid users. Check the latest studies of Acetylsalicylic acid.

What is Definity?

Definity has active ingredients of perflutren. eHealthMe is studying from 4,853 Definity users. Check the latest studies of Definity.



On Jul, 16, 2026

36 people who take Acetylsalicylic acid and Definity together, and have interactions are studied.

Acetylsalicylic acid and Definity drug interactions.

What are the common drug interactions of Acetylsalicylic Acid and Definity, by gender? *:

female:

  1. Anxiety
  2. Dyspnoea (difficult or laboured respiration)
  3. Anaphylactic reaction (serious allergic reaction)
  4. Nervousness
  5. Chest pain
  6. Feeling hot
  7. Pain in extremity
  8. Headache (pain in head)
  9. Left ventricular dysfunction
  10. Muscle spasms (muscle contraction)

male:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Flushing (the warm, red condition of human skin)
  3. Hyperhidrosis (abnormally increased sweating)
  4. Hypotension (abnormally low blood pressure)
  5. Pain in extremity
  6. Pruritus (severe itching of the skin)
  7. Acute myocardial infarction (acute heart attack)
  8. Bradycardia (abnormally slow heart action)
  9. Respiratory failure (inadequate gas exchange by the respiratory system)
  10. Asthenia (weakness)

What are the common drug interactions of Acetylsalicylic Acid and Definity, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anaphylactic reaction (serious allergic reaction)

40-49:

  1. Eye pruritus (eye itching)
  2. Headache (pain in head)
  3. Hypersensitivity
  4. Left ventricular dysfunction
  5. Nausea (feeling of having an urge to vomit)
  6. Rash erythematous (redness of the skin)
  7. Rash generalised (rash on most of body parts)
  8. Urticaria (rash of round, red welts on the skin that itch intensely)
  9. Vomiting
  10. Anaphylactic reaction (serious allergic reaction)

50-59:

  1. Drug hypersensitivity
  2. Flushing (the warm, red condition of human skin)
  3. Nausea (feeling of having an urge to vomit)
  4. Asthenia (weakness)
  5. Dizziness
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Dyspnoea (difficult or laboured respiration)
  8. Hypotension (abnormally low blood pressure)
  9. Pruritus (severe itching of the skin)
  10. Rash

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Pain in extremity
  3. Acute myocardial infarction (acute heart attack)
  4. Bradycardia (abnormally slow heart action)
  5. Chest pain
  6. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  7. Hypotension (abnormally low blood pressure)
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Syncope (loss of consciousness with an inability to maintain postural tone)
  10. Burning sensation

* Approximation only. Some reports may have incomplete information.

Do you take Acetylsalicylic acid and Definity?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acetylsalicylic acid and Definity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acetylsalicylic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Definity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acetylsalicylic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Definity and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on aspirin and perflutren (the active ingredients of Acetylsalicylic acid and Definity, respectively), and Acetylsalicylic acid and Definity (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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