Acidophilus and Combigan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Acidophilus (lactobacillus) and Combigan (brimonidine tartrate; timolol maleate). Common drug interactions include alopecia among females and aplasia pure red cell among males.
The phase IV clinical study analyzes what interactions people have when they take Acidophilus and Combigan. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Acidophilus?
Acidophilus has active ingredients of lactobacillus. It is often used in digestive. eHealthMe is studying from 8,440 Acidophilus users. Check the latest studies of Acidophilus.
What is Combigan?
Combigan has active ingredients of brimonidine tartrate; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 7,810 Combigan users. Check the latest studies of Combigan.
20 people who take Acidophilus and Combigan together, and have interactions are studied.

What are the common drug interactions of Acidophilus and Combigan, by gender? *:
female:
- Alopecia (absence of hair from areas of the body)
- Intraocular pressure increased
- Onychoclasis (breaking of the nails)
- Blood pressure diastolic decreased
- Dyspnoea (difficult or laboured respiration)
- Gait disturbance
- Muscular weakness (muscle weakness)
- Asthenia (weakness)
- Blood glucose increased
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
male:
- Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
- Blood erythropoietin increased
- Confusional state
- Death
- Diarrhoea
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Epistaxis (bleed from the nose)
- Influenza like illness
- Intervertebral discitis (infection in the intervertebral disc space)
What are the common drug interactions of Acidophilus and Combigan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Essential tremor
- Nephrolithiasis (calculi in the kidneys)
30-39:
n/a
40-49:
n/a
50-59:
- Alopecia (absence of hair from areas of the body)
- Intraocular pressure increased
- Onychoclasis (breaking of the nails)
- Blood glucose increased
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
60+:
- Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
- Blood erythropoietin increased
- Asthenia (weakness)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Death
- Hair colour changes
- Hypoaesthesia (reduced sense of touch or sensation)
- Malaise (a feeling of general discomfort or uneasiness)
- Oral herpes (viral infection of mouth)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
What are the existing conditions these people have? *
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 15.00%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 15.00%
- Cerebral Palsy: 3 people, 15.00%
- Multiple Myeloma (cancer of the plasma cells): 3 people, 15.00%
- Skin Disorder (skin disease): 2 people, 10.00%
- Chest Pain: 2 people, 10.00%
- Pain: 2 people, 10.00%
- Stress And Anxiety: 2 people, 10.00%
- High Blood Pressure: 2 people, 10.00%
- Hypersensitivity: 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Acidophilus and Combigan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Acidophilus (8,440 reports)
- Combigan (7,810 reports)
Browse all drug interactions of Acidophilus and Combigan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Acidophilus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Combigan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acidophilus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Combigan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lactobacillus and brimonidine tartrate; timolol maleate (the active ingredients of Acidophilus and Combigan, respectively), and Acidophilus and Combigan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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