Aciphex and Colecalciferol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aciphex (rabeprazole sodium) and Colecalciferol (cholecalciferol). Common drug interactions include headache among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Aciphex and Colecalciferol. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Aciphex?

Aciphex has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 25,301 Aciphex users. Check the latest studies of Aciphex.

What is Colecalciferol?

Colecalciferol has active ingredients of cholecalciferol. eHealthMe is studying from 21,262 Colecalciferol users. Check the latest studies of Colecalciferol.



On Aug, 12, 2026

26 people who take Aciphex and Colecalciferol together, and have interactions are studied.

Aciphex and Colecalciferol drug interactions.

What are the common drug interactions of Aciphex and Colecalciferol, by gender? *:

female:

  1. Headache (pain in head)
  2. Peripheral swelling
  3. Urinary tract infection
  4. Visual impairment
  5. Weight increased
  6. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  7. Immune system disorder
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Abdominal pain upper
  10. Accident

male:

  1. Chronic kidney disease
  2. Blindness unilateral
  3. Full blood count decreased
  4. Platelet count decreased

What are the common drug interactions of Aciphex and Colecalciferol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Abdominal pain upper

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

50-59:

  1. Chronic kidney disease
  2. Adhesion
  3. Blindness unilateral
  4. Constipation
  5. Dyspepsia (indigestion)
  6. Flatulence (flatus expelled through the anus)
  7. Gallbladder disorder
  8. Nausea (feeling of having an urge to vomit)
  9. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  10. Volvulus (obstruction caused by twisting of the stomach or intestine)

60+:

  1. Influenza
  2. Cellulitis (infection under the skin)
  3. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  4. Immune system disorder
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Anxiety
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  8. Death
  9. Full blood count decreased
  10. Myalgia (muscle pain)

What are the existing conditions these people have? *

  1. Blood Pressure Abnormal: 7 people, 26.92%
  2. Urinary Tract Disorder: 5 people, 19.23%
  3. High Blood Pressure: 5 people, 19.23%
  4. Depression: 4 people, 15.38%
  5. Pain: 3 people, 11.54%
  6. Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 11.54%
  7. Rickets (softening of bones): 3 people, 11.54%
  8. High Blood Cholesterol: 3 people, 11.54%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 11.54%
  10. Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Aciphex and Colecalciferol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Aciphex and Colecalciferol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aciphex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Colecalciferol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aciphex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colecalciferol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on rabeprazole sodium and cholecalciferol (the active ingredients of Aciphex and Colecalciferol, respectively), and Aciphex and Colecalciferol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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