Aciphex and Mevacor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aciphex (rabeprazole sodium) and Mevacor (lovastatin). Common drug interactions include aortic valve incompetence among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Aciphex and Mevacor. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Aciphex?

Aciphex has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 25,301 Aciphex users. Check the latest studies of Aciphex.

What is Mevacor?

Mevacor has active ingredients of lovastatin. It is often used in high blood cholesterol. eHealthMe is studying from 4,988 Mevacor users. Check the latest studies of Mevacor.

On Jul, 26, 2026

48 people who take Aciphex and Mevacor together, and have interactions are studied.

What are the common drug interactions of Aciphex and Mevacor, by gender? *:

female:

Aortic valve incompetence
Bone disorder
Bruxism (habitual grinding of the teeth, typically during sleep)
Erythema (redness of the skin)
Gingivitis (inflammation of gums)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Impaired healing
Injury
Muscle spasms (muscle contraction)
Pain

male:

Chronic kidney disease
Renal injury (kidney injury)
Gout (uric acid crystals building up in the body)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cerebral haemorrhage (bleeding within the brain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cystitis (inflammation of the wall of the bladder)
Dizziness
Dyslipidaemia (abnormal amount of lipids)
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Aciphex and Mevacor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease

50-59:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pleural effusion (water on the lungs)
Anxiety
Biliary colic
Bone disorder
Bruxism (habitual grinding of the teeth, typically during sleep)
Cardiac failure congestive
Electrocardiogram qt prolonged
Gingivitis (inflammation of gums)

60+:

Chronic kidney disease
Renal injury (kidney injury)
Toothache (tooth pain)
Herpes simplex (herpes simplex is a common viral infection)
Mouth ulceration (mouth ulcers)
Swelling face
Abdominal pain upper
Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

High Blood Pressure: 29 people, 60.42%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 10 people, 20.83%
Pain: 9 people, 18.75%
Breast Cancer Metastatic: 9 people, 18.75%
Renal Disorder (kidney disease): 6 people, 12.50%
Cardiac Disorder: 6 people, 12.50%
Gastric Ulcer (stomach ulcer): 6 people, 12.50%
Anaemia (lack of blood): 6 people, 12.50%
Gout (uric acid crystals building up in the body): 6 people, 12.50%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 10.42%

* Approximation only. Some reports may have incomplete information.

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