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Propulsid and Oesophageal spasm - a phase IV clinical study of FDA data

Summary:

Oesophageal spasm is reported as a side effect among people who take Propulsid (cisapride monohydrate), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Prilosec, and have Abdominal discomfort.

The phase IV clinical study analyzes which people have Oesophageal spasm when taking Propulsid. It is created by eHealthMe based on reports of 8,120 people who have side effects when taking Propulsid from the FDA, and is updated regularly.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

What is Oesophageal spasm?

Oesophageal spasm (contraction of oesophagus) is found to be associated with 389 drugs and 473 conditions by eHealthMe. Check the latest studies of Oesophageal spasm.

On Jul, 26, 2026

8,120 people reported to have side effects when taking Propulsid.
Among them, 15 people (0.18%) have Oesophageal spasm.

Could Propulsid cause Oesophageal spasm?

Among these 15 people:

How long have people been on Propulsid when they have Oesophageal spasm? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

What is the gender of people who have Oesophageal spasm when taking Propulsid? *

  • female: 85.71 %
  • male: 14.29 %

What is the age of people who have Oesophageal spasm when taking Propulsid? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 33.33 %
  • 40-49: 16.67 %
  • 50-59: 8.33 %
  • 60+: 41.67 %

What are other drugs people take besides Propulsid? *

  1. Celebrex: 5 people, 33.33%
  2. Prilosec: 5 people, 33.33%
  3. Prevacid: 3 people, 20.00%
  4. Albuterol: 3 people, 20.00%
  5. Aricept: 3 people, 20.00%
  6. Biaxin: 3 people, 20.00%
  7. Zocor: 2 people, 13.33%
  8. Omnicef: 2 people, 13.33%
  9. Nasacort: 2 people, 13.33%
  10. Miacalcin: 2 people, 13.33%

What are other side effects people have besides Oesophageal spasm? *

  1. Fatigue (feeling of tiredness): 6 people, 40.00%
  2. Blood Glucose Decreased: 5 people, 33.33%
  3. Chest Pain: 5 people, 33.33%
  4. Swallowing Difficulty: 5 people, 33.33%
  5. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 4 people, 26.67%
  6. Weakness: 4 people, 26.67%
  7. Feeling Abnormal: 4 people, 26.67%
  8. Blood Magnesium Decreased: 4 people, 26.67%
  9. Nausea (feeling of having an urge to vomit): 4 people, 26.67%
  10. Panic Disorder: 3 people, 20.00%

What are the existing conditions these people have? *

  1. Abdominal Discomfort: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Propulsid and have Oesophageal spasm?

- Check whether Oesophageal spasm is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Propulsid:

Oesophageal spasm treatments and more:

How severe was Oesophageal spasm and when was it recovered:

Expand to all the drugs that have ingredients of cisapride monohydrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Propulsid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oesophageal spasm:

Browse all the conditions that are associated with Oesophageal spasm:

How the study uses the data?

The study uses data from the FDA. It is based on cisapride monohydrate (the active ingredients of Propulsid) and Propulsid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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