Acth and Valium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acth (corticotropin) and Valium (diazepam). Common drug interactions include gait disturbance among females and respiratory distress among males.

The phase IV clinical study analyzes what interactions people have when they take Acth and Valium. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Acth?

Acth has active ingredients of corticotropin. eHealthMe is studying from 5,402 Acth users. Check the latest studies of Acth.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.

On Jul, 20, 2026

47 people who take Acth and Valium together, and have interactions are studied.

What are the common drug interactions of Acth and Valium, by gender? *:

female:

Gait disturbance
Glucose urine present
Hemiparesis (weakness on one side of the body)
Hyperhidrosis (abnormally increased sweating)
Hypothalamo-pituitary disorder (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Infusion related reaction
Loss of control of legs
Metamorphopsia (a type of distorted vision in which a grid of straight lines appears wavy and parts of the grid may appear blank)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

male:

Respiratory distress (difficulty in breathing)
General physical health deterioration (weak health status)
Anaemia (lack of blood)
Blood glucose increased
Drug ineffective
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscular weakness (muscle weakness)
Affect lability (emotional incontinence)
Aggression
Alopecia (absence of hair from areas of the body)

What are the common drug interactions of Acth and Valium, by age (0-1 to 60+)? *:

0-1:

Respiratory distress (difficulty in breathing)
Respiratory disorder (respiratory disease)
Drug effect decreased
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Glaucoma (increased fluid pressure in the eye with vision loss)
Lacrimation increased
Papilloedema (optic disc swelling)
Red eye
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Strabismus (a disorder in which the two eyes do not line up in the same direction)

2-9:

n/a

10-19:

n/a

20-29:

Appendicitis (inflammation of the appendix)
Dizziness
Fatigue (feeling of tiredness)
Abdominal discomfort
Abdominal pain upper
Dyspepsia (indigestion)

30-39:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Asthenia (weakness)
Balance disorder
Cardiac flutter (abnormal heart rhythm)
Chest discomfort
Dizziness
Fall
Fatigue (feeling of tiredness)
Feeling drunk
Gait disturbance

40-49:

General physical health deterioration (weak health status)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Limb discomfort (discomfort in leg)
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Pain
Pain in extremity
Relapsing-remitting multiple sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged)

50-59:

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Arthralgia (joint pain)
Blood glucose increased
Drug ineffective
Fluid retention (an abnormal accumulation of fluid in the blood)
Frequent bowel movements
Influenza like illness
Liver disorder (liver diseases)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Tremor (trembling or shaking movements in one or more parts of your body)

60+:

Asthenia (weakness)
Dysphagia (a condition in which swallowing is difficult or painful)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Hypoaesthesia (reduced sense of touch or sensation)
Muscular weakness (muscle weakness)
Diarrhoea
Adverse event
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood pressure fluctuation
Blood pressure increased

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 21 people, 44.68%
Infantile Spasms: 8 people, 17.02%
Gait Disturbance: 8 people, 17.02%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 8.51%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 6.38%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 3 people, 6.38%
Polyarthritis (arthritis which involves 5 or more joints simultaneously): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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