Acthar and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acthar (corticotropin) and Cyclophosphamide (cyclophosphamide). Common drug interactions include mucosal inflammation among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Acthar and Cyclophosphamide. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Acthar?

Acthar has active ingredients of corticotropin. eHealthMe is studying from 4,948 Acthar users. Check the latest studies of Acthar.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

On Jul, 13, 2026

19 people who take Acthar and Cyclophosphamide together, and have interactions are studied.

Acthar and Cyclophosphamide drug interactions.

What are the common drug interactions of Acthar and Cyclophosphamide, by gender? *:

female:

Mucosal inflammation (infection of mucous membrane)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Skin irritation
Infusion site pruritus (severe itching at infusion site)
Infusion site rash
Infusion site urticaria (rash of round, red welts on the skin at infusion site)
Tooth disorder (tooth disease)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

Asthenia (weakness)
Bladder cancer recurrent
Renal failure (kidney dysfunction)
Weight increased
Blood albumin decreased
Blood pressure decreased
Disease recurrence
Fluid retention (an abnormal accumulation of fluid in the blood)
Generalised oedema (swelling all over the body)
Haemorrhage (bleeding)

What are the common drug interactions of Acthar and Cyclophosphamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Neuropathy peripheral (surface nerve damage)
Nocardiosis (an infectious disease affecting either the lungs or whole body)
Pancreatitis acute (sudden inflammation of pancreas)
Granuloma (a small area of inflammation due to tissue injury)
Inflammation
Leukaemoid reaction (elevated white blood cell count, or leukocytosis, that is a physiological response to stress or infection)
Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Abdominal abscess (collection of pus in abdomen)
Confusional state

20-29:

Blood albumin decreased
Generalised oedema (swelling all over the body)
Renal failure (kidney dysfunction)

30-39:

Drug ineffective

40-49:

Speech disorder
Swelling face
Viith nerve paralysis
Viral infection
Abasia (inability to walk)
Aphasia (damage to the parts of the brain that control language)
Asthenia (weakness)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drooling (drop saliva uncontrollably from the mouth)
Dysphagia (a condition in which swallowing is difficult or painful)

50-59:

Abdominal distension
Abdominal pain
Benign breast neoplasm (benign (non-cancerous) tumours of the breast)
Bone loss
Cardiac failure congestive
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chills (felling of cold)
Crepitations (noises are produced by the rubbing of parts one against the other)
Cyst (a closed sac)
Deformity (disfigurement)

60+:

n/a

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 7 people, 36.84%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 3 people, 15.79%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 10.53%
Nocardia Infection (a bacterial infection that usually starts in the lungs. it may spread to other organ systems): 2 people, 10.53%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.26%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 5.26%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Acthar and Cyclophosphamide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously