Estradiol and Methylphenidate hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Estradiol (estradiol) and Methylphenidate hydrochloride (methylphenidate hydrochloride). Common drug interactions include nasopharyngitis among females and electrocardiogram qt prolonged among males.

The phase IV clinical study analyzes what interactions people have when they take Estradiol and Methylphenidate hydrochloride. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Estradiol?

Estradiol has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 18,986 Estradiol users. Check the latest studies of Estradiol.

What is Methylphenidate hydrochloride?

Methylphenidate hydrochloride has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 6,822 Methylphenidate hydrochloride users. Check the latest studies of Methylphenidate hydrochloride.

On Jul, 13, 2026

17 people who take Estradiol and Methylphenidate hydrochloride together, and have interactions are studied.

Estradiol and Methylphenidate hydrochloride drug interactions.

What are the common drug interactions of Estradiol and Methylphenidate Hydrochloride, by gender? *:

female:

Nasopharyngitis (inflammation of the nasopharynx)
Cataract (clouding of the lens inside the eye)
Chills (felling of cold)
Colour blindness (inability to view some colour)
Cystitis (inflammation of the wall of the bladder)
Diplopia (double vision)
Discomfort
Drug ineffective
Drug resistance (reduction in effectiveness of a drug)
Dyskinesia (abnormality or impairment of voluntary movement)

male:

Electrocardiogram qt prolonged

What are the common drug interactions of Estradiol and Methylphenidate Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Electrocardiogram qt prolonged

30-39:

n/a

40-49:

Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood pressure increased
Calculus urinary (stone in urinary system)
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Contusion (a type of hematoma of tissue in which capillaries)
Depression
Dizziness
Heart rate increased
Hypertension (high blood pressure)

50-59:

Eosinophilic pneumonia acute (eosinophil accumulates in the lung-acute)

60+:

Pain
Nausea (feeling of having an urge to vomit)
Nephrolithiasis (calculi in the kidneys)
Renal colic (renal pain)
Renal impairment (severely reduced kidney function)
Weight decreased
Hospitalisation
Road traffic accident

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 29.41%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 17.65%
Immunodeficiency Common Variable: 3 people, 17.65%
Idiopathic Urticaria (allergic reactions, presence of hives with unknown cause): 2 people, 11.76%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 11.76%
Fatigue (feeling of tiredness): 1 person, 5.88%
Back Pain: 1 person, 5.88%
Bladder Spasm: 1 person, 5.88%
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 1 person, 5.88%
Constipation: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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