Acthar and Morphine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acthar (corticotropin) and Morphine (morphine sulfate). Common drug interactions include pyrexia among females and alopecia among males.

The phase IV clinical study analyzes what interactions people have when they take Acthar and Morphine. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Acthar?

Acthar has active ingredients of corticotropin. eHealthMe is studying from 4,948 Acthar users. Check the latest studies of Acthar.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,914 Morphine users. Check the latest studies of Morphine.



On Aug, 12, 2026

33 people who take Acthar and Morphine together, and have interactions are studied.

Acthar and Morphine drug interactions.

What are the common drug interactions of Acthar and Morphine, by gender? *:

female:

  1. Pyrexia (fever)
  2. Injection site pruritus (severe itching at injection site)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Diarrhoea
  5. Fall
  6. Headache (pain in head)
  7. Abdominal pain
  8. Bacteraemia (presence of bacteria in the blood)
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Chronic kidney disease

male:

  1. Alopecia (absence of hair from areas of the body)
  2. Hyperhidrosis (abnormally increased sweating)
  3. Osteochondrosis (a family of orthopaedic diseases of the joint that occur in children and adolescents)
  4. Weight increased
  5. Aphasia (damage to the parts of the brain that control language)
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Meningitis cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  8. Muscle spasms (muscle contraction)
  9. Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas)
  10. Skin irritation

What are the common drug interactions of Acthar and Morphine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Skin irritation
  2. Weight increased
  3. Alopecia (absence of hair from areas of the body)
  4. Hyperhidrosis (abnormally increased sweating)
  5. Osteochondrosis (a family of orthopaedic diseases of the joint that occur in children and adolescents)

40-49:

  1. Headache (pain in head)
  2. Nausea (feeling of having an urge to vomit)
  3. Drug ineffective
  4. Insomnia (sleeplessness)
  5. Rash
  6. Anaphylactic reaction (serious allergic reaction)
  7. Chest pain
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Dyspnoea (difficult or laboured respiration)
  10. Oedema peripheral (superficial swelling)

50-59:

  1. Abdominal pain
  2. Bacteraemia (presence of bacteria in the blood)
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Chronic kidney disease
  5. Constipation
  6. Device occlusion
  7. Diarrhoea
  8. Escherichia urinary tract infection (urinary tract infection by escherichia coli)
  9. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  10. Haematuria (presence of blood in urine)

60+:

  1. Fall
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Intervertebral disc degeneration (spinal disc degeneration)
  5. Lethargy (tiredness)
  6. Pancreatic enzymes increased
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Pyrexia (fever)
  9. Vocal cord paresis
  10. Vomiting

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 27.27%
  2. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 8 people, 24.24%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 24.24%
  4. Muscle Spasms (muscle contraction): 6 people, 18.18%
  5. High Blood Pressure: 6 people, 18.18%
  6. Stress And Anxiety: 6 people, 18.18%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 15.15%
  8. Asthma: 5 people, 15.15%
  9. Chest Pain: 5 people, 15.15%
  10. Dry Eyes (lack of adequate tears): 5 people, 15.15%

* Approximation only. Some reports may have incomplete information.

Do you take Acthar and Morphine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acthar and Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acthar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acthar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on corticotropin and morphine sulfate (the active ingredients of Acthar and Morphine, respectively), and Acthar and Morphine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: