Acthar and Vitamin d3 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acthar (corticotropin) and Vitamin d3 (cholecalciferol). Common drug interactions include stent placement among females and insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Acthar and Vitamin d3. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Acthar?

Acthar has active ingredients of corticotropin. eHealthMe is studying from 4,948 Acthar users. Check the latest studies of Acthar.

What is Vitamin d3?

Vitamin d3 has active ingredients of cholecalciferol. It is often used in heart health. eHealthMe is studying from 32,172 Vitamin d3 users. Check the latest studies of Vitamin d3.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

62 people who take Acthar and Vitamin d3 together, and have interactions are studied.

Acthar and Vitamin d3 drug interactions.

What are the common drug interactions of Acthar and Vitamin D3, by gender? *:

female:

Stent placement
Urine abnormality
Vision blurred
White blood cell count increased
Adverse reaction
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blood creatinine increased
Blood potassium decreased

male:

Insomnia (sleeplessness)
Chronic kidney disease
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Urinary tract infection
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Injection site bruising
Injection site erythema (redness at injection site)
Macrocytosis (enlargement of red blood cells with near-constant haemoglobin concentration)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Urinary tract infection staphylococcal

What are the common drug interactions of Acthar and Vitamin D3, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

30-39:

Drug ineffective
Optic neuritis (optic nerve inflammation)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Injection site erythema (redness at injection site)
Insomnia (sleeplessness)
Pyrexia (fever)
Anaemia (lack of blood)
Infection
Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
Pain

40-49:

Proteinuria (presence of protein in the urine)
Urine abnormality
Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
Anaemia (lack of blood)
Arthropathy
Blood creatinine increased
Blood glucose increased
Dyspnoea (difficult or laboured respiration)
Infusion site hypersensitivity
Peripheral swelling

50-59:

Urinary tract infection staphylococcal
Vision blurred
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)
Blood glucose increased
Burning sensation
Dehydration (dryness resulting from the removal of water)
Disturbance in attention
Feeling cold
Feeling jittery

60+:

Headache (pain in head)
Erythema (redness of the skin)
Pain
Swelling
Abdominal discomfort
Back pain
Benign prostatic hyperplasia (benign enlargement of the prostate)
Calculus bladder (bladder stone)
Depression
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 20 people, 32.26%
Pain: 11 people, 17.74%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 12.90%
High Blood Pressure: 5 people, 8.06%
High Blood Cholesterol: 5 people, 8.06%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 8.06%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 6.45%
Renal Disorder (kidney disease): 4 people, 6.45%
Panic Disorder: 4 people, 6.45%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Acthar and Vitamin d3?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously