Actiq and Lasix drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Actiq (fentanyl citrate) and Lasix (furosemide). Common drug interactions include ejection fraction decreased among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Actiq and Lasix. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.
What is Actiq?
Actiq has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 27,583 Actiq users. Check the latest studies of Actiq.
What is Lasix?
Lasix has active ingredients of furosemide. It is often used in swelling. eHealthMe is studying from 210,439 Lasix users. Check the latest studies of Lasix.
77 people who take Actiq and Lasix together, and have interactions are studied.

What are the common drug interactions of Actiq and Lasix, by gender? *:
female:
- Ejection fraction decreased (systolic heart failure)
- Febrile neutropenia (fever with reduced white blood cells)
- Pneumonia
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Oedema (fluid collection in tissue)
- International normalised ratio decreased
- Jugular vein thrombosis (clot in jugular vein)
- Constipation
- Depression
male:
- Diarrhoea
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Hypoxia (low oxygen in tissues)
- Oedema peripheral (superficial swelling)
- Pulmonary embolism (blockage of the main artery of the lung)
- Actinomycosis (infection that causes sores, or abscesses)
- Alveolar osteitis (complication of wound healing following extraction of a tooth)
- Arthralgia (joint pain)
- Back pain
What are the common drug interactions of Actiq and Lasix, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Application site oedema
- Infection
- Lymphadenopathy (disease or enlargement of lymph nodes)
20-29:
n/a
30-39:
- Dizziness
- Glossodynia (a burning or painful sensation in the tongue)
- Nausea (feeling of having an urge to vomit)
- Neurological symptom (symptoms of nervous system disease)
- Pruritus (severe itching of the skin)
- Skin ulcer
- Tongue blistering
- Vomiting
40-49:
- Diarrhoea
- Hypokalaemia (low potassium)
- Aspartate aminotransferase increased
- Liver carcinoma ruptured (ruptured liver cancer tumour)
- Abdominal pain
- Hepatic failure (liver failure)
- Myopathy (a muscular disease in which the muscle fibres do not function)
- Neuromyopathy (disease of both muscles and nerves)
- International normalised ratio decreased
- Jugular vein thrombosis (clot in jugular vein)
50-59:
- Incisional drainage
- Infection
- Inflammation
- Malignant pleural effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung)
- Metastatic neoplasm (spreadable cancer tumour)
- Oedema peripheral (superficial swelling)
- Oral disorder (mouth disease)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Osteomyelitis (infection of bone)
- Pain in extremity
60+:
- Abdominal pain
- Asthenia (weakness)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Fall
- Hip fracture
- Hyperkalaemia (damage to or disease of the kidney)
- Oedema (fluid collection in tissue)
- Pain in extremity
- Respiration (transport of oxygen from the outside air to the cells within tissues)
- Blood glucose increased
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 17 people, 22.08%
- Headache (pain in head): 15 people, 19.48%
- Abdominal Pain: 14 people, 18.18%
- High Blood Pressure: 14 people, 18.18%
- Hepatic Neoplasm Malignant (liver cancer): 12 people, 15.58%
- Hepatitis B: 12 people, 15.58%
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 12 people, 15.58%
- Oedema (fluid collection in tissue): 12 people, 15.58%
- Metastases To Bone (cancer spreads to bone): 10 people, 12.99%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 10 people, 12.99%
* Approximation only. Some reports may have incomplete information.
Do you take Actiq and Lasix?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Actiq and Lasix:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Actiq:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lasix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actiq and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lasix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
How the study uses the data?
The study uses data from the FDA. It is based on fentanyl citrate and furosemide (the active ingredients of Actiq and Lasix, respectively), and Actiq and Lasix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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