Activase and Cipro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Activase (alteplase) and Cipro (ciprofloxacin hydrochloride). Common drug interactions include rash among females and haemoglobin decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Activase and Cipro. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Activase?

Activase has active ingredients of alteplase. eHealthMe is studying from 7,526 Activase users. Check the latest studies of Activase.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

On Jul, 19, 2026

36 people who take Activase and Cipro together, and have interactions are studied.

What are the common drug interactions of Activase and Cipro, by gender? *:

female:

Rash
Renal tubular necrosis (death of kidney tubules)
Squamous cell carcinoma (a cancer of a kind of epithelial cell)
Weight increased
Asthenia (weakness)
Bradycardia (abnormally slow heart action)
Dizziness
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hyperkeratosis (thickening of the outer layer of the skin)

male:

Haemoglobin decreased
Dyspnoea (difficult or laboured respiration)
Productive cough
Pulmonary congestion (congestion in the lungs)
Rhinorrhoea (watery mucus discharge from the nose)
Sputum increased
Vitamin d deficiency
White blood cell count increased
Anaemia (lack of blood)
Drug ineffective

What are the common drug interactions of Activase and Cipro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Vitamin d deficiency
White blood cell count increased
Blood alkaline phosphatase increased
Chest discomfort
Dyspnoea (difficult or laboured respiration)
Forced expiratory volume decreased (decreased lung expired air volume)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Haemoglobin decreased
Heart rate increased
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

30-39:

n/a

40-49:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Chronic kidney disease
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Lacrimation increased
Lymphoma (cancer that begins in immune system cells)
Neoplasm progression (growth of tumour)
Renal failure (kidney dysfunction)

50-59:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Asthenia (weakness)
Anaemia (lack of blood)

60+:

Hypotension (abnormally low blood pressure)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Weight increased
Bradycardia (abnormally slow heart action)
Febrile neutropenia (fever with reduced white blood cells)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pyrexia (fever)
Rigors (an episode of shaking or exaggerated shivering)
Dyspnoea (difficult or laboured respiration)
Abdominal pain

What are the existing conditions these people have? *

Pain: 11 people, 30.56%
Multiple Myeloma (cancer of the plasma cells): 10 people, 27.78%
Constipation: 8 people, 22.22%
Nausea (feeling of having an urge to vomit): 8 people, 22.22%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 7 people, 19.44%
Nausea And Vomiting: 5 people, 13.89%
Headache (pain in head): 4 people, 11.11%
Indigestion: 4 people, 11.11%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 11.11%
Stress And Anxiety: 4 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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