Activella and Wellbutrin sr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Activella (estradiol; norethindrone acetate) and Wellbutrin sr (bupropion hydrochloride). Common drug interactions include dizziness among females.

The phase IV clinical study analyzes what interactions people have when they take Activella and Wellbutrin sr. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Activella?

Activella has active ingredients of estradiol; norethindrone acetate. It is often used in menopause. eHealthMe is studying from 1,971 Activella users. Check the latest studies of Activella.

What is Wellbutrin sr?

Wellbutrin sr has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 13,112 Wellbutrin sr users. Check the latest studies of Wellbutrin sr.

On Jul, 23, 2026

12 people who take Activella and Wellbutrin sr together, and have interactions are studied.

Activella and Wellbutrin sr drug interactions.

What are the common drug interactions of Activella and Wellbutrin Sr, by gender? *:

female:

Dizziness
Breast cancer
Cerebellar haemorrhage (bleeding in cerebeller)
Cerebral ventricle dilatation (enlargement of ventricle of brain)
Colonoscopy
Diplopia (double vision)
Head injury
Headache (pain in head)
Plantar fasciitis (painful inflammatory process of the plantar fascia)
Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)

male:

n/a

What are the common drug interactions of Activella and Wellbutrin Sr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood glucose decreased
Decreased appetite
Dizziness
Fatigue (feeling of tiredness)
Food aversion (we reject certain foods for a reason)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Nervousness

50-59:

Breast cancer
Cardiac failure congestive
Colonoscopy
Diplopia (double vision)
Dizziness
Dysarthria (speech disorder)
Head injury
Headache (pain in head)
Plantar fasciitis (painful inflammatory process of the plantar fascia)
Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)

60+:

n/a

What are the existing conditions these people have? *

Breast Cancer: 4 people, 33.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 25.00%
Type 2 Diabetes: 1 person, 8.33%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 8.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
Menopausal Depression (depression due to hormonal changes after stop of menses): 1 person, 8.33%
Back Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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