Actonel and Pataday drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Actonel (risedronate sodium) and Pataday (olopatadine hydrochloride). Common drug interactions include rash among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Actonel and Pataday. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Actonel?
Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.
What is Pataday?
Pataday has active ingredients of olopatadine hydrochloride. It is often used in allergies. eHealthMe is studying from 8,288 Pataday users. Check the latest studies of Pataday.
11 people who take Actonel and Pataday together, and have interactions are studied.

What are the common drug interactions of Actonel and Pataday, by gender? *:
female:
- Rash
- Status asthmaticus (a asthma attack not responds to regular medicines)
- Anaemia (lack of blood)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Chronic kidney disease
- Epicondylitis (tennis elbow)
- Fall
- Femur fracture
- Foot fracture
- Fracture nonunion (permanent failure of healing following a broken bone)
male:
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
What are the common drug interactions of Actonel and Pataday, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Status asthmaticus (a asthma attack not responds to regular medicines)
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Kidney infection
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Epicondylitis (tennis elbow)
- Fall
- Femur fracture
- Foot fracture
- Fracture nonunion (permanent failure of healing following a broken bone)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Oral lichen planus (a chronic inflammatory disease that causes bilateral white striations, papules, or plaques on the buccal mucosa)
What are the existing conditions these people have? *
- Pain: 2 people, 18.18%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 18.18%
- Infection: 2 people, 18.18%
- High Blood Pressure: 2 people, 18.18%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 18.18%
- Asthma: 2 people, 18.18%
- Psoriasis (immune-mediated disease that affects the skin): 1 person, 9.09%
- Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 9.09%
- Oedema (fluid collection in tissue): 1 person, 9.09%
- Obstructive Airways Disorder (a progressive disease that makes it hard to breathe): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Actonel and Pataday?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Actonel and Pataday:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Actonel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pataday:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actonel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pataday and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
- Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
- Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
- Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on risedronate sodium and olopatadine hydrochloride (the active ingredients of Actonel and Pataday, respectively), and Actonel and Pataday (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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