Acyclovir and Hycodan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Acyclovir (acyclovir) and Hycodan (homatropine methylbromide; hydrocodone bitartrate). Common drug interactions include hypoaesthesia among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Acyclovir and Hycodan. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Acyclovir?
Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.
What is Hycodan?
Hycodan has active ingredients of homatropine methylbromide; hydrocodone bitartrate. It is often used in cough. eHealthMe is studying from 769 Hycodan users. Check the latest studies of Hycodan.
18 people who take Acyclovir and Hycodan together, and have interactions are studied.

What are the common drug interactions of Acyclovir and Hycodan, by gender? *:
female:
- Hypoaesthesia (reduced sense of touch or sensation)
- Abdominal pain
- Chest discomfort
- Constipation
- Diarrhoea
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Food poisoning (poison in food)
- Gastrointestinal motility disorder (abnormal intestinal contractions)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hyperhidrosis (abnormally increased sweating)
male:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Chest tightness
- Dehydration (dryness resulting from the removal of water)
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Haemoglobin decreased
- Loin pain (pain originates from kidney)
- Muscle strain (an injury to a muscle in which the muscle fibres tear)
- Nausea (feeling of having an urge to vomit)
- Neuropathy peripheral (surface nerve damage)
What are the common drug interactions of Acyclovir and Hycodan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Blood creatinine increased
- Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
- Cachexia (loss of weight)
- Chest tightness
- Dehydration (dryness resulting from the removal of water)
- Dyspnoea (difficult or laboured respiration)
- Loin pain (pain originates from kidney)
- Nausea (feeling of having an urge to vomit)
- Oesophageal reflux (moving the food downwards)
- Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
40-49:
n/a
50-59:
- Dyspnoea (difficult or laboured respiration)
- Chest pain
- Hypoaesthesia (reduced sense of touch or sensation)
- Pneumonia
- Rectal haemorrhage (bleeding from anus)
- Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
- Back pain
- Burning sensation
- Coronary artery stenosis (narrowing of coronary artery)
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
60+:
- Abdominal pain
- Chest discomfort
- Intercostal neuralgia (inflammation of the intercostal nerves)
- Neuropathy peripheral (surface nerve damage)
- Oral candidiasis (fungal infection of mouth)
- Rash macular (small, flat red spots)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Arthralgia (joint pain)
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 8 people, 44.44%
- Pain: 5 people, 27.78%
- Sleep Disorder: 4 people, 22.22%
- Headache (pain in head): 4 people, 22.22%
- Dry Eyes (lack of adequate tears): 4 people, 22.22%
- Pneumonia: 2 people, 11.11%
- Nausea (feeling of having an urge to vomit): 2 people, 11.11%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 11.11%
- Stress And Anxiety: 1 person, 5.56%
- Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Acyclovir and Hycodan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Acyclovir and Hycodan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Acyclovir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Hycodan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acyclovir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hycodan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on acyclovir and homatropine methylbromide; hydrocodone bitartrate (the active ingredients of Acyclovir and Hycodan, respectively), and Acyclovir and Hycodan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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