Adalat and Simulect drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adalat (nifedipine) and Simulect (basiliximab). Common drug interactions include white blood cell disorder among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Adalat and Simulect. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Adalat?

Adalat has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 20,940 Adalat users. Check the latest studies of Adalat.

What is Simulect?

Simulect has active ingredients of basiliximab. eHealthMe is studying from 3,861 Simulect users. Check the latest studies of Simulect.



On Aug, 08, 2026

67 people who take Adalat and Simulect together, and have interactions are studied.

Adalat and Simulect drug interactions.

What are the common drug interactions of Adalat and Simulect, by gender? *:

female:

  1. White blood cell disorder
  2. Wound infection staphylococcal
  3. Wound secretion
  4. Bacterial test positive
  5. Hip arthroplasty
  6. Haemoglobin decreased
  7. Renal impairment (severely reduced kidney function)
  8. Urine output decreased
  9. Capillary leak syndrome (capillary leaks plasma)
  10. Cytomegalovirus infection

male:

  1. Pyrexia (fever)
  2. Blood creatinine increased
  3. Impaired healing
  4. Wound decomposition
  5. Proteinuria (presence of protein in the urine)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Oedema peripheral (superficial swelling)
  8. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  9. Cytomegalovirus test positive
  10. Herpes zoster

What are the common drug interactions of Adalat and Simulect, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Capillary leak syndrome (capillary leaks plasma)
  2. Pyrexia (fever)
  3. Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
  4. Ascites (accumulation of fluid in the abdominal cavity)
  5. Blood pressure fluctuation
  6. Cardiac arrest
  7. Cardiovascular disorder (heart diseases)
  8. General physical health deterioration (weak health status)
  9. Haemodynamic instability (disturbances in the blood movement in our body)
  10. Pericardial effusion (fluid around the heart)

10-19:

  1. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  2. Coagulopathy (blood's ability to clot is impaired)
  3. Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
  4. Multi-organ failure (multisystem organ failure)
  5. Renal failure (kidney dysfunction)
  6. Respiratory failure (inadequate gas exchange by the respiratory system)
  7. Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
  8. Bone marrow failure
  9. Lung infection
  10. Agitation postoperative

20-29:

n/a

30-39:

  1. Blood creatinine increased
  2. Renal disorder (kidney disease)
  3. Abscess (pus)
  4. Chronic allograft nephropathy (failure of kidney transplant)
  5. Effusion (an escape of fluid into a body cavity)
  6. Fluid retention (an abnormal accumulation of fluid in the blood)
  7. Impaired healing
  8. Nephropathy (damage to or disease of a kidney)
  9. Pyrexia (fever)
  10. Wound decomposition

40-49:

  1. Pneumonia bacterial (pneumonia associated with bacterial infection)
  2. Small intestinal haemorrhage (bleeding from small intestine)
  3. Transplant rejection (a transplant material is not worked)
  4. Pyrexia (fever)
  5. Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
  6. Cytomegalovirus infection
  7. Blood creatinine increased
  8. C-reactive protein increased
  9. Decreased appetite
  10. Duodenitis (inflammation of the duodenum)

50-59:

  1. Gait disturbance
  2. Osteonecrosis (death of bone)
  3. White blood cell disorder
  4. Wound infection staphylococcal
  5. Wound secretion
  6. Bacterial test positive
  7. Hip arthroplasty
  8. Kidney transplant rejection
  9. Haemoglobin decreased
  10. Cytomegalovirus infection

60+:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Oedema peripheral (superficial swelling)
  3. Proteinuria (presence of protein in the urine)
  4. Influenza
  5. Renal disorder (kidney disease)
  6. Anuria (failure of the kidneys to produce urine)
  7. Hydronephrosis (water inside the kidney)
  8. Kidney transplant rejection

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 10 people, 14.93%
  2. Lung Infection: 6 people, 8.96%
  3. Renovascular Hypertension (a syndrome which consists of high blood pressure caused by the kidneys hormonal response): 5 people, 7.46%
  4. Osteoporosis (bones weak and more likely to break): 5 people, 7.46%
  5. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 5 people, 7.46%
  6. Enlarged Prostate: 5 people, 7.46%
  7. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 5 people, 7.46%
  8. Constipation: 5 people, 7.46%
  9. Acute Graft Versus Host Disease (acute complication following an allogeneic tissue/blood transplant): 5 people, 7.46%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Adalat and Simulect:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adalat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Simulect:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adalat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Simulect and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nifedipine and basiliximab (the active ingredients of Adalat and Simulect, respectively), and Adalat and Simulect (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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