Adcirca and Ziagen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Adcirca (tadalafil) and Ziagen (abacavir sulfate). Common drug interactions include diarrhoea among females and brain natriuretic peptide increased among males.
The phase IV clinical study analyzes what interactions people have when they take Adcirca and Ziagen. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Adcirca?
Adcirca has active ingredients of tadalafil. It is often used in pulmonary hypertension. eHealthMe is studying from 54,957 Adcirca users. Check the latest studies of Adcirca.
What is Ziagen?
Ziagen has active ingredients of abacavir sulfate. It is often used in hiv infection. eHealthMe is studying from 7,626 Ziagen users. Check the latest studies of Ziagen.
11 people who take Adcirca and Ziagen together, and have interactions are studied.

What are the common drug interactions of Adcirca and Ziagen, by gender? *:
female:
- Diarrhoea
- Gastrointestinal ulcer haemorrhage (bleeding ulcer of digestive system)
- Lymph gland infection
- Right ventricular failure (right half of the heart fails to work)
- Weight decreased
male:
- Brain natriuretic peptide increased
- Hypoxia (low oxygen in tissues)
- Oxygen saturation decreased
- Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
- Disease progression
- Back pain
- Chronic kidney disease
- Drug intolerance (drug sensitivity)
- Renal failure (kidney dysfunction)
- Renal impairment (severely reduced kidney function)
What are the common drug interactions of Adcirca and Ziagen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Brain natriuretic peptide increased
- Hypoxia (low oxygen in tissues)
- Oxygen saturation decreased
- Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
- Disease progression
- Back pain
- Chronic kidney disease
- Drug intolerance (drug sensitivity)
- Renal failure (kidney dysfunction)
- Renal impairment (severely reduced kidney function)
60+:
n/a
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 81.82%
- Cor Pulmonale Chronic (long lasting enlargement of the right ventricle of the heart): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Adcirca and Ziagen?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Adcirca and Ziagen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Adcirca:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ziagen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Adcirca and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ziagen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on tadalafil and abacavir sulfate (the active ingredients of Adcirca and Ziagen, respectively), and Adcirca and Ziagen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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