Onglyza and Compazine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Onglyza (saxagliptin hydrochloride) and Compazine (prochlorperazine maleate). Common drug interactions include drug effect delayed among females and mental status changes among males.
The phase IV clinical study analyzes what interactions people have when they take Onglyza and Compazine. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Onglyza?
Onglyza has active ingredients of saxagliptin hydrochloride. It is often used in diabetes. eHealthMe is studying from 8,638 Onglyza users. Check the latest studies of Onglyza.
What is Compazine?
Compazine has active ingredients of prochlorperazine maleate. It is often used in nausea and vomiting. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.
11 people who take Onglyza and Compazine together, and have interactions are studied.

What are the common drug interactions of Onglyza and Compazine, by gender? *:
female:
- Drug effect delayed
- Hepatic pain (pain in liver)
- Limb crushing injury (crushing injury of upper limb)
- Mitochondrial myopathy (the muscle fibres do not function due to damage of mitochondria)
- Post lumbar puncture syndrome
- Road traffic accident
- Uterine pain
- Abdominal mass (localized enlargement or swelling in the human abdomen)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cystitis (inflammation of the wall of the bladder)
male:
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Pleural effusion (water on the lungs)
What are the common drug interactions of Onglyza and Compazine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Bipolar disorder (mood disorder)
- Drug effect delayed
- Hepatic pain (pain in liver)
- Limb crushing injury (crushing injury of upper limb)
- Mitochondrial myopathy (the muscle fibres do not function due to damage of mitochondria)
- Post lumbar puncture syndrome
- Road traffic accident
- Uterine pain
- Abdominal mass (localized enlargement or swelling in the human abdomen)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
50-59:
n/a
60+:
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Pleural effusion (water on the lungs)
- Asthma
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 7 people, 63.64%
- Migraine (headache): 4 people, 36.36%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 36.36%
- Musculoskeletal Chest Pain (pain in chest muscle or nerve or bones): 4 people, 36.36%
- Muscle Aches (muscle pain): 4 people, 36.36%
- Pain: 3 people, 27.27%
- Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 3 people, 27.27%
- Allergic Rhinitis: 2 people, 18.18%
- Burkitt Lymphoma (cancer of the lymphatic system): 2 people, 18.18%
- High Blood Pressure: 2 people, 18.18%
* Approximation only. Some reports may have incomplete information.
Do you take Onglyza and Compazine?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Onglyza and Compazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Onglyza:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Compazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Onglyza and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Compazine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on saxagliptin hydrochloride and prochlorperazine maleate (the active ingredients of Onglyza and Compazine, respectively), and Onglyza and Compazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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