Lexapro and Dofetilide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Dofetilide (dofetilide). Common drug interactions include memory impairment among females and cardiac failure acute among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Dofetilide. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

What is Dofetilide?

Dofetilide has active ingredients of dofetilide. eHealthMe is studying from 2,646 Dofetilide users. Check the latest studies of Dofetilide.



On Aug, 01, 2026

13 people who take Lexapro and Dofetilide together, and have interactions are studied.

Lexapro and Dofetilide drug interactions.

What are the common drug interactions of Lexapro and Dofetilide, by gender? *:

female:

  1. Memory impairment
  2. Abdominal discomfort
  3. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  4. Back pain
  5. Fatigue (feeling of tiredness)
  6. Headache (pain in head)
  7. Insomnia (sleeplessness)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Pain in extremity
  10. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

male:

  1. Cardiac failure acute
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Death
  4. Paroxysmal arrhythmia
  5. Renal failure (kidney dysfunction)
  6. Blood urine present
  7. Chronic kidney disease
  8. Rectal haemorrhage (bleeding from anus)
  9. Renal injury (kidney injury)
  10. Urinary tract infection

What are the common drug interactions of Lexapro and Dofetilide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal discomfort
  2. Back pain
  3. Fatigue (feeling of tiredness)
  4. Headache (pain in head)
  5. Insomnia (sleeplessness)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Memory impairment
  8. Pain in extremity
  9. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  10. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)

50-59:

  1. Renal failure (kidney dysfunction)
  2. Chronic kidney disease
  3. Renal injury (kidney injury)

60+:

  1. Cardiac failure acute
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Syncope (loss of consciousness with an inability to maintain postural tone)
  4. Weight decreased
  5. Death
  6. Dizziness
  7. Fall
  8. Memory impairment
  9. Paroxysmal arrhythmia
  10. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 69.23%
  2. Weight Decreased: 2 people, 15.38%
  3. Thyroid Diseases: 2 people, 15.38%
  4. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 15.38%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 15.38%
  6. Vitamin D Decreased: 1 person, 7.69%
  7. Swelling: 1 person, 7.69%
  8. Stress And Anxiety: 1 person, 7.69%
  9. Stable Angina (a constant chest pain): 1 person, 7.69%
  10. Pain: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lexapro and Dofetilide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dofetilide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lexapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dofetilide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate and dofetilide (the active ingredients of Lexapro and Dofetilide, respectively), and Lexapro and Dofetilide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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