Adderall 10 and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall 10 (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Profen (ibuprofen). Common drug interactions include chest pain among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall 10 and Profen. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall 10?

Adderall 10 has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 5,182 Adderall 10 users. Check the latest studies of Adderall 10.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 15, 2026

57 people who take Adderall 10 and Profen together, and have interactions are studied.

Adderall 10 and Profen drug interactions.

What are the common drug interactions of Adderall 10 and Profen, by gender? *:

female:

Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depressed level of consciousness
Drug ineffective
Emotional disorder
Gallbladder pain
Hyperlipidaemia (presence of excess lipids in the blood)
Hypertension (high blood pressure)
Insomnia (sleeplessness)

male:

Arthralgia (joint pain)
Chronic fatigue syndrome (disorder that causes extreme fatigue)
Irritable bowel syndrome
Multi-organ disorder (multiple organ disease)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Proctitis ulcerative (inflammation of the rectum and anus ulcerative)
Lip dry
Disturbance in attention
Rectal haemorrhage (bleeding from anus)
Drug abuser

What are the common drug interactions of Adderall 10 and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Accidental exposure
Agitation (state of anxiety or nervous excitement)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Hallucination, visual (seeing things that aren't there)

10-19:

Abdominal pain upper
Anaphylactic reaction (serious allergic reaction)
Bleeding time prolonged
Cholecystitis acute (rapid infection of gallbladder)
Cholecystitis chronic (long lasting infection of gallbladder)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Fibroma (tumours that are composed of fibrous or connective tissue)
Gallbladder disorder
Glossodynia (a burning or painful sensation in the tongue)

20-29:

Arthralgia (joint pain)
Chronic fatigue syndrome (disorder that causes extreme fatigue)
Colitis (inflammation of colon)
Colitis ulcerative (inflammation of colon with ulcer)
Dry skin
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Inflammatory bowel disease
Intestinal haemorrhage (bleeding from intestine)

30-39:

Injury
Arthralgia (joint pain)
Asthenia (weakness)
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Cellulitis (infection under the skin)
Cholecystitis chronic (long lasting infection of gallbladder)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Emotional distress
Fall

40-49:

Injury
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary infarction (death of a small area of lung)
Abdominal pain upper
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pancreatitis acute (sudden inflammation of pancreas)
Thrombosis (formation of a blood clot inside a blood vessel)
Tooth extraction

50-59:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypoaesthesia (reduced sense of touch or sensation)
Muscle spasms (muscle contraction)
Muscle twitching
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Blood cholesterol increased
Emotional disorder

60+:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaesthetic complication
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Dry mouth
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Heart rate increased
Muscle spasms (muscle contraction)
Surgery

What are the existing conditions these people have? *

Asthma: 11 people, 19.30%
Acne (skin problems that cause pimples): 7 people, 12.28%
Premenstrual Syndrome: 5 people, 8.77%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 7.02%
Sleep Disorder: 3 people, 5.26%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 5.26%
Menstruation Irregular: 3 people, 5.26%
High Blood Pressure: 3 people, 5.26%
Depression: 3 people, 5.26%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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