Adderall and Cobalamin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Cobalamin (vitamin b12). Common drug interactions include abdominal discomfort among females and therapeutic response unexpected among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Cobalamin. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,226 Adderall users. Check the latest studies of Adderall.

What is Cobalamin?

Cobalamin has active ingredients of vitamin b12. eHealthMe is studying from 3,429 Cobalamin users. Check the latest studies of Cobalamin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

30 people who take Adderall and Cobalamin together, and have interactions are studied.

Adderall and Cobalamin drug interactions.

What are the common drug interactions of Adderall and Cobalamin, by gender? *:

female:

Abdominal discomfort
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cystitis (inflammation of the wall of the bladder)
Defaecation urgency (a sudden compelling urge to defecate)
Ear infection
Gastrointestinal hypomotility (less activity of the intestinal tract)
Influenza like illness
Infusion site bruising
Infusion site swelling
Mastoiditis (infection of mastoid bone)

male:

Therapeutic response unexpected
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

What are the common drug interactions of Adderall and Cobalamin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Lyme disease (a bacterial infection that is spread to humans by infected ticks)
Alopecia (absence of hair from areas of the body)
Dandruff
Emotional distress
Folliculitis (infection of hair root)
Paradoxical drug reaction

30-39:

n/a

40-49:

Abdominal discomfort
Aptyalism (deficiency or absence of saliva)
Fatigue (feeling of tiredness)
Glucose urine present
Hyperhidrosis (abnormally increased sweating)
Hypothalamo-pituitary disorder (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function)
Pyrexia (fever)
Surgery
Tooth extraction
Arthritis (form of joint disorder that involves inflammation of one or more joints)

50-59:

Disease recurrence
Nervousness
Throat tightness

60+:

Asthenia (weakness)
Back pain
Gait disturbance
Lethargy (tiredness)
Limb discomfort (discomfort in leg)
Memory impairment
Neck injury
Somnolence (a state of near-sleep, a strong desire for sleep)
Stress
Dry skin

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 33.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 26.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 16.67%
Immunodeficiency Common Variable: 3 people, 10.00%
Primary Immunodeficiency Syndrome: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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