Adderall and Doxylamine succinate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Doxylamine succinate (doxylamine succinate). Common drug interactions include sinusitis among females and neuralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Doxylamine succinate. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,226 Adderall users. Check the latest studies of Adderall.

What is Doxylamine succinate?

Doxylamine succinate has active ingredients of doxylamine succinate. It is often used in insomnia. eHealthMe is studying from 2,851 Doxylamine succinate users. Check the latest studies of Doxylamine succinate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

19 people who take Adderall and Doxylamine succinate together, and have interactions are studied.

Adderall and Doxylamine succinate drug interactions.

What are the common drug interactions of Adderall and Doxylamine Succinate, by gender? *:

female:

Sinusitis (inflammation of sinus)
Oral herpes (viral infection of mouth)
Fatigue (feeling of tiredness)
Fungal infection
Headache (pain in head)
Mastitis (inflammation of breast)
Uterine infection
Anxiety
Pruritus (severe itching of the skin)
Vulvovaginal mycotic infection (vulvovaginal fungal infection)

male:

Neuralgia (pain in one or more nerves)
Somnolence (a state of near-sleep, a strong desire for sleep)
Empyema (collection of pus in a cavity in the body)
Pericardial effusion (fluid around the heart)
Postoperative wound infection
Diarrhoea
Drug ineffective
Injury
Retinal tear
Seborrhoeic keratosis (noncancerous (benign) skin growths that some people develop as they age. they often appear on the back or chest)

What are the common drug interactions of Adderall and Doxylamine Succinate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Laryngitis (inflammation of the larynx)
Upper respiratory tract infection
Infusion site extravasation (flow of (blood or lymph) from infusion site)

30-39:

Uterine infection
Pruritus (severe itching of the skin)
Vulvovaginal mycotic infection (vulvovaginal fungal infection)
Cough
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Influenza
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Paranasal sinus discomfort
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)

40-49:

Cataplexy (loss of muscle tone accompanied by full conscious awareness)
Sleep attacks

50-59:

Diarrhoea
Drug ineffective
Therapeutic response unexpected

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 42.11%
Immunodeficiency Common Variable: 8 people, 42.11%
Neuralgia (pain in one or more nerves): 4 people, 21.05%
Stress And Anxiety: 2 people, 10.53%
Immunodeficiency: 2 people, 10.53%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 10.53%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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