Adderall and L-cysteine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and L-cysteine (n - acetyl cysteine). Common drug interactions include vertigo among females and apnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and L-cysteine. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is L-cysteine?

L-cysteine has active ingredients of n - acetyl cysteine. eHealthMe is studying from 335 L-cysteine users. Check the latest studies of L-cysteine.



On Jul, 06, 2026

42 people who take Adderall and L-cysteine together, and have interactions are studied.

Adderall and L-cysteine drug interactions.

What are the common drug interactions of Adderall and L-Cysteine, by gender? *:

female:

  1. Vertigo
  2. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  3. Pruritus (severe itching of the skin)
  4. Back pain
  5. Dizziness
  6. Ear congestion
  7. Hot flush (sudden feelings of heat)
  8. Hyperhidrosis (abnormally increased sweating)
  9. Infection
  10. Insomnia (sleeplessness)

male:

  1. Apnoea (suspension of external breathing)
  2. Bladder obstruction
  3. Muscle spasms (muscle contraction)
  4. Road traffic accident
  5. Spinal fracture (fracture in one of vertebrae)
  6. Cataplexy (loss of muscle tone accompanied by full conscious awareness)
  7. Craniocerebral injury (injury to cranium and brain)
  8. Hypersomnia (excessive daytime sleepiness (eds))
  9. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

What are the common drug interactions of Adderall and L-Cysteine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Asthma
  2. Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
  3. Hypersomnia (excessive daytime sleepiness (eds))
  4. Vertigo
  5. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  6. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  7. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  8. Productive cough
  9. Rash
  10. Syncope (loss of consciousness with an inability to maintain postural tone)

30-39:

  1. Insomnia (sleeplessness)
  2. Pruritus (severe itching of the skin)
  3. Scratch
  4. Skin erosion (a discontinuity of the skin)

40-49:

  1. Hyperhidrosis (abnormally increased sweating)
  2. Migraine (headache)
  3. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
  4. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  5. Nasopharyngitis (inflammation of the nasopharynx)
  6. Neck pain
  7. Peripheral swelling
  8. Pruritus (severe itching of the skin)
  9. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  10. Sinus congestion (blockage of sinus)

50-59:

  1. Apnoea (suspension of external breathing)
  2. Bladder obstruction
  3. Muscle spasms (muscle contraction)
  4. Road traffic accident
  5. Spinal fracture (fracture in one of vertebrae)
  6. Cataplexy (loss of muscle tone accompanied by full conscious awareness)

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 39 people, 92.86%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 16 people, 38.10%
  3. Muscle Aches (muscle pain): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Adderall and L-cysteine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Adderall and L-cysteine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of L-cysteine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adderall and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between L-cysteine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate and n - acetyl cysteine (the active ingredients of Adderall and L-cysteine, respectively), and Adderall and L-cysteine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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