Adderall and Lacosamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Lacosamide (lacosamide). Common drug interactions include pain in extremity among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Lacosamide. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Lacosamide?

Lacosamide has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 16,601 Lacosamide users. Check the latest studies of Lacosamide.

On Jul, 06, 2026

17 people who take Adderall and Lacosamide together, and have interactions are studied.

Adderall and Lacosamide drug interactions.

What are the common drug interactions of Adderall and Lacosamide, by gender? *:

female:

Pain in extremity
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Ataxia (loss of full control of bodily movements)
Limb injury
Localised infection (infection at the single location)
Panic attack
Peripheral swelling
Speech disorder
Arthralgia (joint pain)
Hypersensitivity

male:

Death
Sudden unexplained death in epilepsy
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Retroperitoneal haemorrhage (bleeding between the peritoneum and the posterior abdominal wall)
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection
Arrhythmia (irregular heartbeat)
Cardiac disorder
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

What are the common drug interactions of Adderall and Lacosamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Death
Ataxia (loss of full control of bodily movements)
Limb injury
Localised infection (infection at the single location)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pain in extremity
Panic attack
Peripheral swelling
Speech disorder
Contusion (a type of hematoma of tissue in which capillaries)

40-49:

n/a

50-59:

Balance disorder
Dizziness
Drug ineffective
Gait disturbance
Grip strength decreased
Limb discomfort (discomfort in leg)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia

60+:

Urinary tract infection
Arthralgia (joint pain)
Sepsis (a severe blood infection that can lead to organ failure and death)
Hypersensitivity
Pain in extremity
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary thrombosis (scarring in the lungs)
Weight increased
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the existing conditions these people have? *

Back Pain: 8 people, 47.06%
Indigestion: 8 people, 47.06%
Muscle Aches (muscle pain): 5 people, 29.41%
Muscle Spasms (muscle contraction): 3 people, 17.65%
Stress And Anxiety: 3 people, 17.65%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 17.65%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 11.76%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 11.76%
Pain: 2 people, 11.76%
Neuralgia (pain in one or more nerves): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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