Adderall and Lo/ovral drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Lo/ovral (ethinyl estradiol; norgestrel). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Lo/ovral. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,226 Adderall users. Check the latest studies of Adderall.

What is Lo/ovral?

Lo/ovral has active ingredients of ethinyl estradiol; norgestrel. It is often used in birth control. eHealthMe is studying from 1,298 Lo/ovral users. Check the latest studies of Lo/ovral.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

24 people who take Adderall and Lo/ovral together, and have interactions are studied.

Adderall and Lo/ovral drug interactions.

What are the common drug interactions of Adderall and Lo/Ovral, by gender? *:

female:

Fatigue (feeling of tiredness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Heart rate irregular
Immunodeficiency
Nodule on extremity (a small rock or mineral cluster on hands or legs)
Stress
Weight increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Swelling
Vomiting

male:

n/a

What are the common drug interactions of Adderall and Lo/Ovral, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Fatigue (feeling of tiredness)
Heart rate irregular
Stress
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Abnormal dreams
Dyspepsia (indigestion)

30-39:

Joint swelling
Oedema peripheral (superficial swelling)
Nodule on extremity (a small rock or mineral cluster on hands or legs)
Weight increased
Pruritus (severe itching of the skin)
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

Somnolence (a state of near-sleep, a strong desire for sleep)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 17 people, 70.83%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 45.83%
Panic Disorder: 7 people, 29.17%
Stress And Anxiety: 5 people, 20.83%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 20.83%
Seasonal Allergy (allergic condition due to certain season): 4 people, 16.67%
Neuralgia (pain in one or more nerves): 4 people, 16.67%
Drowsiness: 4 people, 16.67%
Bipolar Disorder (mood disorder): 4 people, 16.67%
Apathy: 4 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Adderall and Lo/ovral?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously