Adderall and Lumryz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Lumryz (sodium oxybate). Common drug interactions include night sweats among females and insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Lumryz. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Lumryz?

Lumryz has active ingredients of sodium oxybate. eHealthMe is studying from 744 Lumryz users. Check the latest studies of Lumryz.

On Jul, 26, 2026

100 people who take Adderall and Lumryz together, and have interactions are studied.

What are the common drug interactions of Adderall and Lumryz, by gender? *:

female:

Night sweats (sweating in night)
Photopsia (presence of perceived flashes of light)
Respiratory rate decreased (less breathing rate/min)
Seborrhoea (a disease of the sebaceous glands characterized by excessive secretion of sebum)
Sedation
Skin warm
Depressed level of consciousness
Dry mouth
Panic attack
Stress

male:

Insomnia (sleeplessness)
Initial insomnia (feeling of inadequate or poor-quality sleep)
Vomiting
Memory impairment
Nocturia (the need to get up in the night to urinate)
Sleep attacks
Sleep paralysis (waking up and unable to move or speak)
Abdominal discomfort
Abdominal pain upper
Affect lability (emotional incontinence)

What are the common drug interactions of Adderall and Lumryz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal discomfort
Cardiac disorder
Chest discomfort
Dizziness
Drug ineffective
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Panic attack
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sinusitis (inflammation of sinus)

20-29:

Vomiting
Insomnia (sleeplessness)
Migraine (headache)
Nightmare (unpleasant dream)
Respiratory tract infection
Sleep paralysis (waking up and unable to move or speak)
Terminal insomnia (a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired)
Abdominal discomfort
Anxiety
Decreased appetite

30-39:

Insomnia (sleeplessness)
Drug ineffective
Vomiting
Disturbance in attention
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Headache (pain in head)
Initial insomnia (feeling of inadequate or poor-quality sleep)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Nocturia (the need to get up in the night to urinate)

40-49:

Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Fatigue (feeling of tiredness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Poor quality sleep
Nausea (feeling of having an urge to vomit)
Nocturia (the need to get up in the night to urinate)
Drug ineffective
Bruxism (habitual grinding of the teeth, typically during sleep)
Burning sensation
Dehydration (dryness resulting from the removal of water)

50-59:

Back pain
Chest pain
Drug ineffective
Fluid retention (an abnormal accumulation of fluid in the blood)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Peripheral swelling
Weight increased

60+:

Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Dizziness
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Pain
Sedation
Sleep talking (talking during sleeping)
Spinal column injury (spinal cord bone injury)
Terminal insomnia (a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired)
Tinnitus (a ringing in the ears)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 95 people, 95.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 46 people, 46.00%
Drowsiness: 7 people, 7.00%

* Approximation only. Some reports may have incomplete information.

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