Adderall and Mavyret drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Mavyret (glecaprevir; pibrentasvir). Common drug interactions include nausea among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Mavyret. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Mavyret?

Mavyret has active ingredients of glecaprevir; pibrentasvir. eHealthMe is studying from 10,533 Mavyret users. Check the latest studies of Mavyret.

On Jul, 20, 2026

32 people who take Adderall and Mavyret together, and have interactions are studied.

What are the common drug interactions of Adderall and Mavyret, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
Vomiting
Anaphylactic reaction (serious allergic reaction)
Diarrhoea
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Rash

male:

Diarrhoea
Fatigue (feeling of tiredness)
Decreased appetite
Gastric ph decreased
White blood cell count increased
Malaise (a feeling of general discomfort or uneasiness)
Pancreatic carcinoma stage ii (pancreatic cancer stage ii)
Suicide attempt
Dandruff
Skin infection

What are the common drug interactions of Adderall and Mavyret, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diarrhoea
Gastrointestinal pain
General physical health deterioration (weak health status)
Hallucination (an experience involving the perception of something not present)
Hepatic pain (pain in liver)
Visual impairment
Weight decreased
Decreased appetite
Fatigue (feeling of tiredness)
Gastric ph decreased

30-39:

Anaphylactic reaction (serious allergic reaction)
Dysgeusia (disorder of the sense of taste)
Hypoaesthesia (reduced sense of touch or sensation)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Diarrhoea
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Pancreatic carcinoma stage ii (pancreatic cancer stage ii)
Suicide attempt
Agitation (state of anxiety or nervous excitement)

40-49:

Gastric disorder (disease of stomach)
Influenza
Malaise (a feeling of general discomfort or uneasiness)
Rash
Skin infection
Therapeutic response unexpected
Urticaria (rash of round, red welts on the skin that itch intensely)

50-59:

Diarrhoea
Hepatitis c
Nail disorder (disease of nail)
Nausea (feeling of having an urge to vomit)
Rash
Vomiting
Colitis (inflammation of colon)

60+:

Balance disorder
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
Dysarthria (speech disorder)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Syncope (loss of consciousness with an inability to maintain postural tone)
Tremor (trembling or shaking movements in one or more parts of your body)
Visual impairment
Vomiting

What are the existing conditions these people have? *

Hepatitis C: 8 people, 25.00%
Stress And Anxiety: 3 people, 9.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.38%
Disturbance In Attention: 3 people, 9.38%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 6.25%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 6.25%
Hypersensitivity: 2 people, 6.25%
Depression: 2 people, 6.25%
Birth Control: 2 people, 6.25%
Asthma: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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