Adderall and Skyla drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Skyla (levonorgestrel). Common drug interactions include drug ineffective among females.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Skyla. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,225 Adderall users. Check the latest studies of Adderall.

What is Skyla?

Skyla has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 5,452 Skyla users. Check the latest studies of Skyla.

On Aug, 04, 2026

28 people who take Adderall and Skyla together, and have interactions are studied.

What are the common drug interactions of Adderall and Skyla, by gender? *:

female:

Drug ineffective
Pregnancy with contraceptive device
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Dyskinesia (abnormality or impairment of voluntary movement)
Ectopic pregnancy (a pregnancy in which the foetus develops outside the uterus, typically in a fallopian tube)
Fall
Fatigue (feeling of tiredness)
Genital haemorrhage (bleeding from genital)
Hypomenorrhoea (a diminution of the menstrual flow or a shortening of the duration of menstruation)

male:

n/a

What are the common drug interactions of Adderall and Skyla, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Drug ineffective
Fatigue (feeling of tiredness)
Genital haemorrhage (bleeding from genital)
Hypomenorrhoea (a diminution of the menstrual flow or a shortening of the duration of menstruation)
Influenza like illness
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Nausea (feeling of having an urge to vomit)
Post procedural discomfort
Pregnancy with contraceptive device

20-29:

Abdominal pain lower
Anxiety
Drug ineffective
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Hypersensitivity
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Abdominal distension
Abdominal tenderness
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)

30-39:

Decreased appetite
Diarrhoea
Drug ineffective
Ectopic pregnancy (a pregnancy in which the foetus develops outside the uterus, typically in a fallopian tube)
Nausea (feeling of having an urge to vomit)
Panic attack
Physical assault
Pregnancy with contraceptive device
Scratch
Sinus congestion (blockage of sinus)

40-49:

Drug ineffective
Pregnancy with contraceptive device

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 39.29%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 25.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 14.29%
Drowsiness: 3 people, 10.71%
Depression: 3 people, 10.71%
Acne (skin problems that cause pimples): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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